Results 71 to 80 of about 23,434,422 (312)

The effectiveness of aromatherapy on stress management in nurses: a meta-analysis of randomized controlled trials [PDF]

, 2023
M Wang, Huan Zhang, Xiaoli Zeng, Jing-zhi Li   +3 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Surveillance for adverse events following immunization in Hebei Province, China, 2018-2020

Human Vaccines & Immunotherapeutics
The aim of this study was to analyze the incidence and characteristics of adverse events following immunization (AEFI) with post-licensure vaccines used in Hebei province from 2018 to 2020 and to evaluate the safety of vaccines.
Li Sun, Shifan Wang, Yafei Wang, Yihan Wang, Jinghui Wang, Jing Li, Xiaomeng Xu, Junmian Zhang, Yanli Cong, Yu Guo   +9 more
doaj   +1 more source

Cross‐view face recognition via structured dictionary based domain shift

IET Computer Vision, 2015
View variation is a major challenge in face recognition. In this study, the authors propose a novel cross‐view face recognition method by seeking potential intermediate domains between the source and target views to model the connection of varying‐views ...
Xue Chen, Chunheng Wang, Baihua Xiao, Xinyuan Cai   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Efficient attention vision transformers for monocular depth estimation on resource-limited hardware

Scientific Reports
Vision Transformers show important results in the current Deep Learning technological landscape, being able to approach complex and dense tasks, for instance, Monocular Depth Estimation.
Claudio Schiavella, Lorenzo Cirillo, Lorenzo Papa, Paolo Russo, Irene Amerini   +4 more
doaj   +1 more source

A Reproducible Analysis of Sequential Recommender Systems

IEEE Access
Sequential Recommender Systems (SRSs) have emerged as a highly efficient approach to recommendation systems. By leveraging sequential data, SRSs can identify temporal patterns in user behaviour, significantly improving recommendation accuracy and ...
Filippo Betello, Antonio Purificato, Federico Siciliano, Giovanni Trappolini, Andrea Bacciu, Nicola Tonellotto, Fabrizio Silvestri   +6 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Adverse events following immunization of co- and separate administration of DTaP-IPV/Hib vaccines: A real-world comparative study

Human Vaccines & Immunotherapeutics
To fully understand the safety of DTaP-IPV/Hib vaccination, we evaluated the differences between DTaP-IPV/Hib co-administration and separate administration of the DTaP, IPV and Hib vaccines (DTaP+IPV+Hib) based on adverse events following immunization ...
Yiqing Zhu, Li Sun, Yihan Wang, Jinghui Wang, Yafei Wang, Jing Li, Lina Wang, Yu Guo   +7 more
doaj   +1 more source