Results 81 to 90 of about 2,078,436 (263)

A clinical prediction model for central venous catheter-associated bloodstream infections: derivation and validation from the MIMIC-IV cohort

European Journal of Medical Research
Background Central venous catheter-associated bloodstream infections (CVC–BSIs) significantly affect clinical outcomes in critically ill patients. Existing risk prediction models lack comprehensive integration of early clinical indicators.
Bo Song, Guanjun Jiang, Yujia Liu, Dongsheng Cheng   +3 more
doaj   +1 more source

Optimizing maternal and neonatal outcomes through tight control management of inflammatory bowel disease during pregnancy: a pilot feasibility study. [PDF]

Sci Rep, 2023
Jogendran R, O'Connor K, Jeyakumar A, Tandon P, Nguyen GC, Maxwell C, Huang V.   +6 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Adverse events following immunization surveillance on two types of enterovirus 71 vaccines: A real-world comparative study in China

Human Vaccines & Immunotherapeutics
To comprehensively assess the safety and difference of two types of EV71 vaccines: EV71-Vero, produced using Vero cells and EV71-H2, using human diploid cells.
Yiqing Zhu, Yihan Wang, Jinghui Wang, Yafei Wang, Li Sun, Shiheng Cui, Jing Li, Yu Guo   +7 more
doaj   +1 more source

Novel electrochemical biosensor key significance of smart intelligence (IoMT & IoHT) of COVID-19 virus control management. [PDF]

Process Biochem, 2022
Paladhi AG, Manohar M, Pal K, Vallinayagam S, Packirisamy ASB, Bashreer VA, Sai Nandhini R, Ukhurebor KE.   +7 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Relationship between ventilator-associated pneumonia and prognosis among patients in cardiac surgical intensive care units: a retrospective analysis based on the MIMIC database

The Egyptian Journal of Bronchology
Background Ventilator-associated pneumonia (VAP) is a frequent nosocomial infection in patients undergoing cardiac surgery, contributing to prolonged hospitalization and increased healthcare burden.
Bo Song, Guanjun Jiang, Yujia Liu, Dongsheng Cheng   +3 more
doaj   +1 more source

Outbreak control management: Lessons from SARS-CoV-2 infections in 2020-2022 in Hong Kong, an international municipality with high-frequency travelers. [PDF]

MedComm (2020), 2022
Feng Y, Young CH, Lau SH, He ML.
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source