Results 91 to 100 of about 15,001,366 (306)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Indoor Air Wellness: A Predictive Model for Pollution Control Using Advanced AI Techniques

open access: yesIEEE Access
Indoor air quality (IAQ) has a crucial impact on health, yet many spaces suffer from unnoticed pollution. This study introduces “Indoor Air Wellness”, a predictive model that utilizes advanced AI techniques, specifically integrating Kalman ...
Kalyan Chatterjee   +9 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Control Of Compliant Parallel Arm Mechanism [PDF]

open access: yes, 2015
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2006Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2006Bu çalışmada, belirlenen görevleri yerine getirmesi için; esnek paralel kol ...
Tekeş, Ayşe
core  

Formalisation and Implementation of the XACML Access Control Mechanism [PDF]

open access: yes, 2012
We propose a formal account of XACML, an OASIS standard adhering to the Policy Based Access Control model for the specifica- tion and enforcement of access control policies.
R. Pugliese   +8 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Fuzzy Adaptive PID Control of a New Hydraulic Erecting Mechanism [PDF]

open access: yes, 2013
Conventional erecting mechanism is cumbersome and the erecting velocity is slow, so a new hydraulic erecting mechanism is introduced in this paper. But it has two problems.
Xie, Jian; Xi’an Research Inst.   +2 more
core   +1 more source

Application of fractal theory in rockfill rheology

open access: yesShuili Shuiyun Gongcheng Xuebao, 2017
The rockfill material crushes during the process of rheology and the fractal dimension of rockfill material varies with time. Based on the basic rule of rheological process of coarse-grained soils, the fractal theory is applied into the analysis of ...
BIAN Shihai, LI Guoying, MI Zhankuan
doaj   +1 more source

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