Results 121 to 130 of about 15,001,366 (306)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Antikythera Mechanism PTMs brightened 43-57, Fragment A

, 2019
These PTMs were constructed from images of all known remaining surfaces of the Antikythera Mechanism fragments housed in the National Archaeological Museum in Athens, Greece.
Antikythera Mechanism Research Project
core   +21 more sources

Liquor control decision; State of Connecticut, Department of Consumer Protection, before the Liquor Control Commission

, 2006
Irregular; Some issues lack docket or permit number.; Prepared for Connecticut. Liquor Control Commission by Connecticut.
Connecticut. Liquor Control Commission.
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Adaptive repetitive control of a compact disc mechanism

, 1995
Radial track following of a compact disc player servo mechanism is severely exposed to periodic disturbances, induced by the eccentric rotation of the disc.
Hof, Van den, P.M.J., Steinbuch, M., Hof, Van den, P.M.J.; id_orcid, Dötsch, H.G.M., Smakman, H.T., Steinbuch, M.; id_orcid   +5 more
core  

Microstructures and mechanical properties of laser welded joints in Ce-containing rare earth magnesium alloys

Journal of Aeronautical Materials
During the welding thermal cycle，changes in the distribution and morphology of precipitates within the heat-affected zone (HAZ) often lead to typical softening，making HAZ the weakest region of the welded joints.
CAO Jun, CHEN Yanfei, XIONG Zhilin, LI Sijia   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Performance characteristics of the lever-van shock absorber with the hinge-lever control mechanism

Trudy Odesskogo Politehničeskogo Universiteta, 2020
The article presents a fundamentally new example of a passive lever-blade shock absorber with an articulated lever mechanism for controlling its operating characteristic, the use of which is effective as part of the torsion bar suspension of a tracked ...
Ігор Іванович Сидоренко, Ігор Валентинович Прокопович, Світлана Юріївна Дмітрієва, Марія Василівна Королькова, Софія Вікторівна Ковбан   +4 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Antikythera Mechanism PTMs brightened 35-42, Fragment B

, 2019
These PTMs were constructed from images of all known remaining surfaces of the Antikythera Mechanism fragments housed in the National Archaeological Museum in Athens, Greece.
Antikythera Mechanism Research Project
core   +13 more sources