Results 121 to 130 of about 19,379,431 (255)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Control of mechanical systems with constraints: two pendulums case study
, 2008 A method for control of mechanical systems under phase constraints, applicable to energy control of Hamiltonian systems is proposed. The constrained energy control problem for two pendulums by a single control action is studied both analytically and ...
Anayevskiy, M.S. +3 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
American Journal of Public Health, 1920 If we are economically and efficiently to ward off plague we must rid ourselves of the rat. This demands coördination of effort, management, organization and funds. Rat destruction and rat-proofing are preventive measures that fortunately do not involve financial loss, while they will eliminate the dangerous rodent from the homes and environment of ...
openaire +3 more sources
A linguistic control method for posture stabilization of wheeled mobile robot
, 2006 A linguistic control method based on motion description languages for posture stabilization of wheeled mobile robot is presented in this paper. In robotic systems control actions should be selected and executed by the triggering events.
Hua JN(化建宁) +2 more
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 1990 The papers presented at the Symposium covered the areas in aerospace technology where automatic control plays a vital role. These included navigation and guidance, space robotics, flight management systems and satellite orbital control systems.
International Federation of Automatic Control +1 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
, 1990 In the last two decades, the development of specific methodologies for the control of systems described by nonlinear mathematical models has attracted an ever increasing interest.
Isidori, Alberto +2 more
core