Results 131 to 140 of about 70,597 (264)

Genome‐wide identification of MsAlkB family genes and functional analysis of MsALKBH2 as an RNA m6A eraser in alfalfa (Medicago sativa L.) subject to drought stress

Grassland Research, EarlyView.
MsALKBH2 is an mRNA m6A demethylase in alfalfa that is required for enhancing drought tolerance through decreasing ROS content. Abstract Background N6‐methyladenosine (m6A), the most prevalent mRNA modification in plants, plays a pivotal role in developmental processes and stress responses.
Xianglong Zhao, Jie Zhao, Hui Zhang, Yan Li, Chao Sui, Wengang Xie, Zhipeng Liu, Mingjia Chen, Wenxian Liu   +8 more
wiley   +1 more source

Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella Review

Head &Neck, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) represents the most common oral potentially malignant disorder globally, with highly variable reported malignant transformation (MT) rates creating challenges for evidence‐based clinical management. Objective To systematically synthesize evidence on MT prevalence in OL and evaluate potential predictive ...
Mohammed Taib Fatih, Mohammed Khalid Mahmood, Balkees Taha Garib, Yad Mariwan Mohammed Amin, Ranjdar Mahmood Talabani, Tara Ali Rasheed, Handren Ameer Kurda, Balen Hamid Qadir, Zana Fuad Noori, Mohammed Aso Abdulghafor, Ariwan Othman Saeed, Herve Tassery, Delphine Tardivo, Romain Lan   +13 more
wiley   +1 more source

A family case of a rare Xq28 duplication. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Kopytova AE, Tolmacheva EN, Emelina DA, Glotov OS, Miroshnikova VV, Usenko TS, Vasilyeva OY, Makarov IV, Lobanov AD, Mazo GE, Pchelina SN, Lebedev IN.   +11 more
europepmc   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Gene Duplication, Translocation, and Molecular Evolution of <i>Dmrt1</i> and Related Sex-Determining Genes in Anurans. [PDF]

Biomolecules
Shinde SS, Veltsos P, Ma WJ.
europepmc   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

Comparative genomics and expression analysis of polyamine oxidase gene family in Sorghum bicolor reveals functional specialization, gene duplication, and role in drought resilience. [PDF]

BMC Genomics
Ebeed HT.
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Recurrent Duplication, Testis-Biased Expression, and Functional Diversification of <i>Esf2/ABT1</i> Family Genes in <i>Drosophila</i>. [PDF]

Insects
Davydova ED, Kotov AA, Chernizova AV, Yakovleva EY, Olenina LV.   +4 more
europepmc   +1 more source

Cyclin-Specific Control of Ribosomal DNA Segregation

Molecular and Cellular Biology, 2008
M. Sullivan, L. Holt, D. Morgan
semanticscholar   +1 more source