Results 141 to 150 of about 70,597 (264)

Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits

International Journal of Cancer, EarlyView.
What's New? Hepatocellular carcinoma arises from a combination of environmental and genetic factors, with the latter playing a potentially more significant role in nonviral hepatocellular carcinoma. Here, the authors characterized the genetic correlations and heritability between nonviral hepatocellular carcinoma and 901 epidemiologic, behavioral, and ...
Younghun Han, Vikram R. Shaw, Jinyoung Byun, Aaron P. Thrift, Catherine Zhu, Donghui Li, Rikita I. Hatia, Robin Kate Kelley, Sean P. Cleary, Anna S. Lok, Paige M. Bracci, Jennifer B. Permuth, Roxana Bucur, Jennifer Knox, Jian‐Min Yuan, Amit G. Singal, Prasun K. Jalal, R. Mark Ghobrial, Yuko Kono, Dimpy P. Shah, Mindie H. Nguyen, Neehar D. Parikh, Richard Kim, Hui‐Chen Wu, Hashem El‐Serag, Ping Chang, Yun Shin Chun, Jian Gu, Chad Huff, Asif Rashid, Lu‐Yu Hwang, Alison P. Klein, Saira A. Khaderi, Ahmed O. Kaseb, Kathrine A. McGlynn, Lewis R. Roberts, Manal M. Hassan, Christopher I. Amos   +37 more
wiley   +1 more source

FRIGIDA-like gene family in rapeseed: genome-wide analysis and expression analysis to exogenous phytohormones. [PDF]

BMC Plant Biol
Basharat S, Saeed W, Liu P, Waseem M.
europepmc   +1 more source

Loss of METTL3 m6A methyltransferase results in short‐term progression and poor treatment outcome of bladder cancer patients

International Journal of Cancer, EarlyView.
What's New? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala, Stella Koroneou, Maria‐Alexandra Papadimitriou, Konstantina Panoutsopoulou, Konstantinos Soureas, Georgios‐Christos Giagkos, Panagiotis Levis, Dimitrios Linardoutsos, Konstantinos Stravodimos, Margaritis Avgeris, Andreas Scorilas   +10 more
wiley   +1 more source

Olfactory gene dynamics in invasive Indian and non-invasive African malaria vectors at the crossroads of development, infection and resistance. [PDF]

Sci Rep
Sharma A, Dixit B, Goyal B, Harit R, Kumar J, Biswas S, Goswami R, Pandey KC, Emami SN, Chakraborti S.   +9 more
europepmc   +1 more source

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Rare case of PLAG1::RUNX1 fusion mimicking classical t(8;21): the value of optical genome mapping in acute myeloid leukemia. [PDF]

Mol Cytogenet
Assaf N, Alawieh S, Hammoud R, Daudignon A, Luquet I, Lambert J, Terré C.   +6 more
europepmc   +1 more source

Epigenetic Control of Replication Origins

Cell Cycle, 2005
Jing Zhou, Charles M. Chau, Z. Deng, William Stedman, P. Lieberman   +4 more
semanticscholar   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, EarlyView.
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

RNA-seq Splicing Profile of the <i>CDH1</i> Gene and Its Impact on the Clinical Pathogenicity Classification of <i>CDH1</i> Variants: A Description of Alternative and Pathogenic Splicing Patterns. [PDF]

Cancers (Basel)
Sebai M, Tang R, Adnani Y, Fievet A, Cabaret O, Robert de Rancher MA, Auger N, Elaribi Y, Jilani H, Limacher JM, Caron O, Jemaa LB, Rouleau E.   +12 more
europepmc   +1 more source

Segmental duplications and copy-number variation in the human genome.

American Journal of Human Genetics, 2005
A. Sharp, Devin P. Locke, S. McGrath, Ze Cheng, J. Bailey, Rhea U. Vallente, Lisa M. Pertz, Royden A. Clark, S. Schwartz, R. Segraves, V. Oseroff, D. Albertson, D. Pinkel, E. Eichler   +13 more
semanticscholar   +1 more source