Results 161 to 170 of about 130,329 (268)

Cohort profile: The Halmstad University Register on Pupils with Intellectual Disability

JCPP Advances, EarlyView.
Abstract Background Knowledge about the living conditions among people with intellectual disabilities (ID) is globally scarce. Even in countries with good access to registers, this is often partly due to the absence of a single, comprehensive, nationwide register of individuals with ID or the inability to identify all individuals with ID within ...
Eva Jönsson, Carin Staland‐Nyman, Paul Lichtenstein, Magnus Tideman   +3 more
wiley   +1 more source

Genome-wide identification, structural characterization and gene expression analysis of the LEA_2 gene family in faba bean (Vicia Faba L.). [PDF]

BMC Plant Biol
Yin Y, Wang X, Ma H, Chen Q, Tang X, Wu X, Feng S.   +6 more
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Whole-genome sequencing reveals complex structural variations at a major locus linked to pigmented spot sizes in Tianfu goats. [PDF]

BMC Genomics
Guo J, Huang Q, Xiang Q, Wu G, Bian P, Wang X, Li L, Liu GE, Zhang H.   +8 more
europepmc   +1 more source

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho, José Caetano Silva‐Filho, Janaina Lima de Oliveira   +2 more
wiley   +1 more source

Genomic architecture and evolution of heterostyly: new insights from Cordia subcordata (Boraginaceae). [PDF]

Mol Biol Evol
Shi M, Barrett SCH, Zhang Y, Zhang J, Zhao Z, Wang X, Yuan S, Luo Z, Gu S, Li S, Tu T, Zhang D.   +11 more
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

Application of noninvasive prenatal testing-plus in fetal ultrasound cardiovascular abnormalities: An observational study. [PDF]

Medicine (Baltimore)
Jin K, Xu X, Shen S, Hu M, Luo J, Li N.
europepmc   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

Chromothriptic Translocation t(1;18): A Paradigm of Genomic Complexity in a Child with Normal Intellectual Development and Pyridoxine-Dependent Epilepsy. [PDF]

Genes (Basel)
Falsaperla R, Salvo E, Sapuppo A, Barberi C, Sortino V, Fusto G, Rizzo R, Pappalardo XG, Corsello G, Ruggieri M, Romano C, Saccuzzo L, Fichera M, Bonaglia MC.   +13 more
europepmc   +1 more source