Results 11 to 20 of about 70,597 (264)
DDK: The Outsourced Kinase of Chromosome Maintenance
Biology, 2022 Simple Summary To ensure the maintenance of genetic stability prior to cell division a cell’s complement of chromosomes must be duplicated. This requires not only the replication of the chromosomal DNA but also the re-establishment the chromatin ...
P. Gillespie, J. Blow
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Horticulturae, 2022 The transcription factors (TFs) family known as the basic leucine zipper (bZIP) plays a vital role in a variety of biological processes. However, there is no investigation on the bZIP family in the major vegetable crop, eggplant.
Yan Li +5 more
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Unique signatures of natural background radiation on human Y chromosomes from Kerala, India. [PDF]
PLoS ONE, 2009 BackgroundThe most frequently observed major consequences of ionizing radiation are chromosomal lesions and cancers, although the entire genome may be affected.
Sanjay Premi +3 more
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The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes. [PDF]
PLoS ONE, 2017 Quebec Platelet disorder (QPD) is a unique bleeding disorder that markedly increases urokinase plasminogen activator (uPA) in megakaryocytes and platelets but not in plasma or urine.
Catherine P M Hayward +7 more
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Influence of long and short arms of X chromosome on maxillary molar crown morphology. [PDF]
PLoS ONE, 2018 Although genes on the human X chromosome reportedly influence tooth crown morphology, little is known about X chromosome activation or inactivation systems relevant to morphological variations.
Mitsuko Nakayama +4 more
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Tandem repeats and G-rich sequences are enriched at human CNV breakpoints. [PDF]
PLoS ONE, 2014 Chromosome breakage in germline and somatic genomes gives rise to copy number variation (CNV) responsible for genomic disorders and tumorigenesis. DNA sequence is known to play an important role in breakage at chromosome fragile sites; however, the ...
Promita Bose +3 more
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Autism and duplication of 17q12q21.2 by array-CGH: a case report
Revista Paulista de Pediatria, 2023 Objective: Autism spectrum disorder (ASD) affects cognitive development and social interaction on different levels. Genetic and environmental factors are associated with secondary ASD.
Alana Weingartner +10 more
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mBio, 2019 Coordinating chromosome duplication and segregation with cell division is clearly critical for bacterial species with one chromosome. The precise choreography required is even more complex in species with more than one chromosome.
Nelly Dubarry +4 more
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Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups. [PDF]
PLoS ONE, 2015 The human Y chromosome is almost always excluded from genome-wide investigations of copy number variants (CNVs) due to its highly repetitive structure. This chromosome should not be forgotten, not only for its well-known relevance in male fertility, but ...
Martin M Johansson +6 more
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BMC Medical Genetics, 2009 Background Microdeletion of the chromosome 22q11.2 region is the most common genetic aberration among patients with velocardiofacial syndrome (VCFS) but a subset of subjects do not show alterations of this chromosome region.
Estivill Xavier +7 more
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