Results 211 to 220 of about 130,329 (268)

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

Andrology, EarlyView.
Abstract Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier, Jann‐Frederik Cremers, Phillip Schrage, Amelie Körtje, Claudia Krallmann, Sabine Kliesch, Jörg Gromoll, Sandra Laurentino, Michael Zitzmann   +8 more
wiley   +1 more source

Puzzler: scalable one-command platinum-quality genome assembly from HiFi and Hi-C. [PDF]

Bioinform Adv
Merondun J, Yu Q.
europepmc   +1 more source

The Testicular Cancer Consortium (TECAC): Filling Knowledge Gaps in the Genetic Etiology of Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Peter A. Kanetsky, Kristian Almstrup, Svetlana Cherlin, Victoria K. Cortessis, Alberto Ferlin, Jourik A. Gietema, Anna González‐Neira, Tom Grotmol, Robert J. Hamilton, Trine B. Haugen, Lambertus A. Kiemeney, Jung Kim, Csilla Krausz, Davor Lessel, Ragnhild A. Lothe, Kevin T. Nead, Jérémie Nsengimana, Jenny N. Poynter, Ewa Rajpert‐DeMeyts, Lorenzo Richiardi, Stephen M. Schwartz, Rolf I. Skotheim, Douglas R. Stewart, Clare Turnbull, Fredrik Wiklund, Tongzhang Zheng, Katherine L. Nathanson, Katherine A. McGlynn, for the Testicular Cancer Consortium   +28 more
wiley   +1 more source

Unveiling genomic rearrangements in engineered iPSC lines by optical genome mapping. [PDF]

Mol Ther Methods Clin Dev
Finlay D, Hor P, Goldenson BH, Li XH, Murad R, Kaufman DS, Vuori K.   +6 more
europepmc   +1 more source

The association between autism and psychosis and the tools used to measure it: An updated systematic review and meta‐analysis

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Autistic individuals are at increased risk of psychotic experiences and being diagnosed with psychotic disorders. This association may result from methodological issues, including the misinterpretation of psychosis questionnaires by autistic individuals and clinicians' difficulty distinguishing between the conditions.
Michael R. Miles, Dennis Golm, Emma Palmer‐Cooper   +2 more
wiley   +1 more source

Revealing the impact of partial gene duplications in ASH1L: integration of optical genome mapping and RNA sequencing. [PDF]

Mol Cytogenet
Blavier G, Lecoquierre F, Guerrot AM, Hélas GJ, Rondeau S, Boland A, Deleuze JF, Nicolas G, Chambon P, Cassinari K.   +9 more
europepmc   +1 more source

Hypomethylating agents in vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS): A systematic review

British Journal of Haematology, EarlyView.
Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff, Roochi Trikha, Emma M. Groarke, Bhavisha A. Patel   +3 more
wiley   +1 more source

Genome-Wide Identification of the <i>OPR</i> Gene Family in Soybean and Its Expression Pattern Under Salt Stress. [PDF]

Biology (Basel)
Han Z, Zhang X, Sun Y, Lin C, Ding X, Yan H, Zhan Y, Zhang C.   +7 more
europepmc   +1 more source

System level network data and models attack cancer drug resistance

British Journal of Pharmacology, EarlyView.
Drug resistance is responsible for >90% of cancer related deaths. Cancer drug resistance is a system level network phenomenon covering the entire cell. Small‐scale interactomes and signalling network models of drug resistance guide directed drug development.
Márk Kerestély, Dávid Keresztes, Levente Szarka, Borbála M. Kovács, Klára Schulc, Dániel V. Veres, Peter Csermely   +6 more
wiley   +1 more source

Genome-wide analysis of genetic diversity in Anopheles darlingi from Rondônia State, Brazil. [PDF]

Commun Biol
Moss S, Acford-Palmer H, Andrade AO, Manko E, Phelan J, Higgins M, Medeiros JF, Clark TG, Araujo MS, Campino S.   +9 more
europepmc   +1 more source