Results 231 to 240 of about 130,329 (268)

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

Rapid gain and loss of a chromosome drives key morphology and virulence phenotypes in the fungal pathogen Histoplasma. [PDF]

PLoS Biol
Heater S, Voorhies M, Rodriguez RA, English BC, Sil A.   +4 more
europepmc   +1 more source

Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci

Cell Proliferation, EarlyView.
To identify novel imprinted genes, parthenogenetic, androgenetic and biparental human embryonic stem cells and their differentiated neural progenitors were analysed by methylome and transcriptome profiling. This approach uncovered 12 putative novel imprinted genes, including a clustered region on chromosome 19, expanding the current catalogue of ...
Shay Kinreich, Nissim Benvenisty
wiley   +1 more source

Optical genome mapping of a complex structural rearrangement family line on chromosome 18. [PDF]

Hereditas
Cai L, Jiang Y, Zhang N, Chen X.
europepmc   +1 more source

Mainstream or special secondary school for the health, education, and well‐being of adolescents with Down syndrome: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
This systematic review identified three studies comparing education, health, social, and self‐care outcomes among adolescents with Down syndrome who attended either mainstream or special secondary school. Two studies reported improved education outcomes among adolescents in mainstream secondary school.
Julia Shumway, Jill Ellis, Bianca Lucia De Stavola, Ruth Gilbert, Ania Zylbersztejn   +4 more
wiley   +1 more source

Recurrent Duplication, Testis-Biased Expression, and Functional Diversification of <i>Esf2/ABT1</i> Family Genes in <i>Drosophila</i>. [PDF]

Insects
Davydova ED, Kotov AA, Chernizova AV, Yakovleva EY, Olenina LV.   +4 more
europepmc   +1 more source

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

A chromosome-level genome of Astilbe chinensis unveils the evolution of a terpene biosynthetic gene cluster. [PDF]

Nat Commun
Chen F, Yao Y, Zhu H, Hu J, Geng A, Xu Z, Fang X, Cheng W, Zhi Y, Zhang Y, Deng Z, Liu T, Lu L.   +12 more
europepmc   +1 more source

Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi, Haruka Ishibashi, Yukako Nakagami, Yoko Kobayashi Takahashi, Takato Akiba, Masaharu Miyauchi, Naohiro Yamamoto, Ryoichi Inoue, Satoshi Kodama, Takafumi Kubota, Naoto Kuroda   +10 more
wiley   +1 more source

Functional Insights into <i>SlNPF</i>, <i>SlNRT2</i>, and <i>SlAMT</i> Gene Families in Tomato: Leaf Metabolic Performance Controls Root-to-Shoot Nitrogen Partitioning. [PDF]

Plants (Basel)
Ledesma-Valladolid JP, Niño-González MI, Malda-Barrera GX, Flores-Sosa ÁR, Pacheco-Aguilar JR, Nava-Morales GM, Mercado-Silva EM.   +6 more
europepmc   +1 more source