Results 21 to 30 of about 70,597 (264)

Synchronization of a genetic oscillator with the cell division cycle

New Journal of Physics, 2022
Genetic circuits that control specific cellular functions are never fully insulated against influences of other parts of the cell. For example, they are subject to periodic modulation by the cell cycle through volume growth and gene doubling.
Gabriel Knotz, Ulrich Parlitz, Stefan Klumpp   +2 more
doaj   +1 more source

Nuclear pore proteins and the control of genome functions

Genes & Development, 2015
Nuclear pore complexes (NPCs) are composed of several copies of proteins called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the nucleocytoplasmic trafficking of macromolecules, and NPC components influence genome functions ...
Arkaitz Ibarra, M. Hetzer
semanticscholar   +1 more source

Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7

BMC Biology, 2021
Background Copy number variants (CNVs) linked to genes involved in nervous system development or function are often associated with neuropsychiatric disease.
Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner, John N. Constantino, Kristen L. Kroll   +11 more
doaj   +1 more source

Cytomolecular characterization of de novo formed rye B chromosome variants

Molecular Cytogenetics, 2012
Background B chromosomes (Bs) are dispensable elements which occur in many species including rye (Secale cereale). We determined the organization of B variants to obtain insights into the origin of B polymorphisms in rye.
Marques André, Klemme Sonja, Guerra Marcelo, Houben Andreas   +3 more
doaj   +1 more source

Mosaic Xq duplication, or 46,X,der(X)dup(X)(q22.1q22.2)dup(X)(q25q22.3)/ 46,XX at amniocentesis in a pregnancy with a favorable outcome

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: We present mosaic Xq duplication, or 46,X,der(X)dup(X)(q22.1q22.2)dup(X)(q25q22.3)/46,XX at amniocentesis in a pregnancy with a favorable outcome.
Chih-Ping Chen, Tsang-Ming Ko, Schu-Rern Chern, Peih-Shan Wu, Shin-Wen Chen, Fang-Tzu Wu, Yun-Yi Chen, Meng-Shan Lee, Wayseen Wang   +8 more
doaj   +1 more source

DIS3 depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification

Haematologica, 2023
DIS3 gene mutations occur in approximately 10% of patients with multiple myeloma (MM); furthermore, DIS3 expression can be affected by monosomy 13 and del(13q), found in roughly 40% of MM cases. Despite the high incidence of DIS3 mutations and deletions,
Vanessa K. Favasuli, Domenica Ronchetti, Ilaria Silvestris, Noemi Puccio, Giuseppina Fabbiano, Valentina Traini, Katia Todoerti, Silvia Erratico, Alessia Ciarrocchi, Valentina Fragliasso, Domenica Giannandrea, Francesca Tumiatti, Raffaella Chiaramonte, Yvan Torrente, Palma Finelli, Eugenio Morelli, Nikhil C. Munshi, Niccolò Bolli, Antonino Neri, Elisa Taìana   +19 more
doaj   +1 more source

Redefining bacterial origins of replication as centralized information processors

Frontiers in Microbiology, 2015
In this review we stress the differences between eukaryotes and bacteria with respect to their different cell cycles, replication mechanisms and genome organizations.
Gregory eMarczynski, Thomas eRolain, James eTaylor   +2 more
doaj   +1 more source

Genome-Wide Analysis of the Aquaporin Gene Family in chickpea (Cicer arietinum L.)

Frontiers in Plant Science, 2016
Aquaporins (AQPs) are essential membrane proteins that play critical role in the transport of water and many other solutes across cell membranes. In this study, a comprehensive genome-wide analysis identified 40 AQP genes in chickpea (Cicer arietinum L.).
Amit Deokar, Bunyamin Tar'an
doaj   +1 more source

Advanced genetic therapies for the treatment of Rett syndrome: state of the art and future perspectives

Frontiers in Neuroscience, 2023
Loss and gain of functions mutations in the X-linked MECP2 (methyl-CpG-binding protein 2) gene are responsible for a set of generally severe neurological disorders that can affect both genders.
Michela Palmieri, Diego Pozzer, Nicoletta Landsberger, Nicoletta Landsberger   +3 more
doaj   +1 more source

Polyploidy: its consequences and enabling role in plant diversification and evolution

Annals of Botany, 2022
Background Most, if not all, green plant (Virdiplantae) species including angiosperms and ferns are polyploids themselves or have ancient polyploid or whole genome duplication signatures in their genomes.
J. Heslop-Harrison, T. Schwarzacher, Qing Liu   +2 more
semanticscholar   +1 more source