Results 51 to 60 of about 130,329 (268)

Improved reference genome of the arboviral vector Aedes albopictus [PDF]

, 2020
Background: The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. With limited antiviral drugs and vaccines available, vector control is the primary approach to prevent mosquito ...
Akbari, Omar,, Antoshechkin, Igor, Biedler, James,, Bonizzoni, Mariangela, Caccone, Adalgisa, Cosme, Luciano,, Crawford, Jacob,, Failloux, Anna-Bella, Gamez, Stephanie, Ghurye, Jay, Halbach, Rebecca, Jenrette, Jeremy, Johnston, J. Spencer, Karagodin, Dmitry,, Koren, Sergey, Krsticevic, Flavia, Marconcini, Michele, Masri, Reem,, Masterson, Patrick, Miesen, Pascal, Palatini, Umberto, Papathanos, Philippos,, Phillippy, Adam,, Pischedda, Elisa, Powell, Jeffrey, Rhie, Arang, Sharakhova, Maria,, Sharma, Atashi, Thibaud-Nissen, Francoise, Tu, Zhijian, van Rij, Ronald,   +30 more
core   +5 more sources

FCGR Genetic Variation in Two Populations From Ecuador Highlands—Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene

Frontiers in Immunology, 2021
Fcγ receptors (FcγR), cell-surface glycoproteins that bind antigen-IgG complexes, control both humoral and cellular immune responses. The FCGR locus on chromosome 1q23.3 comprises five homologous genes encoding low-affinity FcγRII and FcγRIII, and ...
Manuela Moraru, Adriana Perez-Portilla, Karima Al-Akioui Sanz, Alfonso Blazquez-Moreno, Antonio Arnaiz-Villena, Hugh T. Reyburn, Carlos Vilches   +6 more
doaj   +1 more source

The evolution of IL-4 and IL-13 and their receptor subunits [PDF]

, 2015
Peer ...
Secombes, Christopher J., Wang, Tiehui
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Characterization of high frequency of recombination strains selected by integrative suppression of F’lac in dnaA, gyrA and gyrB temperature sensitive mutants

Journal of Biological Research, 2017
Integration of F’lac plasmid into chromosome of both gyrA(Ts) and gyrB(Ts) cells phenotypically suppress the thermosensitive mutations of the DNA gyrase enzymes.
Eugenio A. Debbia, Anna Marchese
doaj   +1 more source

Transcriptomic and proteomic analysis of pyrethroid resistance in the CKR strain of Aedes aegypti.

PLoS Neglected Tropical Diseases, 2021
Aedes aegypti is an important vector of human viral diseases. This mosquito is distributed globally and thrives in urban environments, making it a serious risk to human health.
Haina Sun, Robert W Mertz, Letícia B Smith, Jeffrey G Scott   +3 more
doaj   +1 more source

Combined Analysis of MicroRNAs and Target Genes Revealed miR156-SPLs and miR172-AP2 Are Involved in a Delayed Flowering Phenomenon After Chromosome Doubling in Black Goji (Lycium ruthencium)

Frontiers in Genetics, 2021
Polyploidy, which is widely distributed in angiosperms, presents extremely valuable commercial applications in plant growth and reproduction. The flower development process of higher plants is essential for genetic improvement.
Shupei Rao, Shupei Rao, Yue Li, Yue Li, Jinhuan Chen, Jinhuan Chen   +5 more
doaj   +1 more source

Joint assembly and genetic mapping of the Atlantic horseshoe crab genome reveals ancient whole genome duplication [PDF]

, 2013
Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral arthropod traits, and are ...
Brockmann, H Jane, Havlak, Paul, Lv, Jie, Nossa, Carlos, Putnam, Nicholas H, Vincent, Kim, Yue, Jia-Xing   +6 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]

, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller, Altamirano, Arechavala, Bicanic, Bicanic, Boeva, Chang, Chen, Dannaoui, DePristo, Drusano, Harrison, Li, Longley, Loyse, Martin, Mayanja-Kizza, McKenna, Molloy, Mondon, Neely, Nixon, Nussbaum, Saag, Sionov, Sionov, Stone, Stott, Stott, Sudan, Wiederhold, Witt   +31 more
core   +1 more source