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STAT1 and Its Crucial Role in the Control of Viral Infections

open access: yesInternational Journal of Molecular Sciences, 2022
The signal transducer and activator of transcription (STAT) 1 protein plays a key role in the immune response against viruses and other pathogens by transducing, in the nucleus, the signal from type I, type II and type III IFNs.
M. Tolomeo, A. Cavalli, A. Cascio
semanticscholar   +1 more source

Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections

open access: yesJournal of Nanobiotechnology, 2021
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to control microbial infections. Although nucleic acid testing is widely deployed for the detection of antibiotic resistant bacteria, the current techniques—mainly
Yuye Wu   +6 more
semanticscholar   +1 more source

Effect of Ventilation System on Spread and Control of Infections (COVID-19) in Indoor Environments: Based on Current Studies

open access: yesAsian Pacific Journal of Environment and Cancer, 2020
Transmission of infectious diseases like SARS-COV-2 by ventilation systems has become an international concern. In this study, an attempt was made to assess the role of ventilation systems in spread and control of SARS-COV-2 in indoor environments.
Mohammad Nourmohammadi   +3 more
doaj   +1 more source

Inhibitory effect of toothbrush monofilament containing surface pre-reacted glass-ionomer (S-PRG) filler on Streptococcus mutans

open access: yesScientific Reports, 2021
The oral environment affects not only oral health, but also general health, and the importance of oral self-care has recently been recognised. Although toothbrushes are the most important self-care product, there are few toothbrushes that have an ...
Saaya Matayoshi   +4 more
doaj   +1 more source

Accuracy of real-time PCR and digital PCR for the monitoring of total HIV DNA under prolonged antiretroviral therapy

open access: yesScientific Reports, 2022
Total HIV DNA is a standard marker to monitor the HIV reservoir in people living with HIV. We investigated HIV DNA quantification accuracy by a real-time PCR kit (qPCR) and digital PCR (dPCR) method within the same set of primers and probes.
Constance Renault   +6 more
doaj   +1 more source

Inflammatory Control of Viral Infection

open access: yesViruses, 2023
Inflammatory responses during virus infection differentially impact the host. Managing inflammatory responses is essential in controlling viral infection and related diseases. Recently, we identified a cellular anti-inflammatory mechanism, RIKA (Repression of IRF3-mediated inhibition of NF-κB activity), which controls viral inflammation and ...
Sukanya Chakravarty   +2 more
openaire   +3 more sources

Glycemic Control and Risk of Infections Among People With Type 1 or Type 2 Diabetes in a Large Primary Care Cohort Study

open access: yesDiabetes Care, 2018
OBJECTIVE Diabetes mellitus (DM) increases the risk of infections, but the effect of better control has not been thoroughly investigated. RESEARCH DESIGN AND METHODS With the use of English primary care data, average glycated hemoglobin (HbA1c) during ...
J. Critchley   +5 more
semanticscholar   +1 more source

West Nile Virus Neuroinfection in Humans: Peripheral Biomarkers of Neuroinflammation and Neuronal Damage

open access: yesViruses, 2022
Among emerging arthropod-borne viruses (arbovirus), West Nile virus (WNV) is a flavivirus that can be associated with severe neuroinvasive infections in humans.
Orianne Constant   +4 more
doaj   +1 more source

Epizootic Situation in the Mongolian Part of the Transboundary Sailugem Natural Plague Focus in 2018

open access: yesПроблемы особо опасных инфекций, 2019
Objective of the study was monitoring of epizootic situation in the Mongolian part of the trans-boundary Sailugem natural plague focus through 2018 for optimization of preventive and anti-epidemic activities to decrease the level of risk of human plague ...
V. M. Korzun   +15 more
doaj   +1 more source

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