Results 41 to 50 of about 3,393,140 (353)

Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It to the Anti-inflammatory M2 Phenotype

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Tuberculosis, a human infectious disease caused by Mycobacterium tuberculosis (M.tb), is still a major cause of morbidity and mortality worldwide. The success of M.tb as a pathogen relies mainly on its ability to divert the host innate immune responses ...
Amira Refai   +4 more
doaj   +1 more source

Fighting viral infections and virus-driven tumors with cytotoxic CD4+ T cells [PDF]

open access: yes, 2017
CD4+ T cells have been and are still largely regarded as the orchestrators of immune responses, being able to differentiate into distinct T helper cell populations based on differentiation signals, transcription factor expression, cytokine secretion, and
Adhikary   +229 more
core   +2 more sources

Comparison of contact patterns relevant for transmission of respiratory pathogens in Thailand and the Netherlands using respondent-driven sampling [PDF]

open access: yes, 2014
Understanding infection dynamics of respiratory diseases requires the identification and quantification of behavioural, social and environmental factors that permit the transmission of these infections between humans.
Anna E. Thorson   +46 more
core   +6 more sources

Mongolian Part of the Transboundary Sailugem Natural Plague Focus in 2017. Communication 1. Epizootic condition

open access: yesПроблемы особо опасных инфекций, 2018
Objective – estimation of current epizootic condition of Mongolian part of transboundary Sailugem natural plague focus. Materials and methods. Epizootiological survey was performed for the area of 2335 km2, 277 mammals and 516 ectoparasites were ...
V. M. Korzun   +17 more
doaj   +1 more source

Inflammasome control of viral infection [PDF]

open access: yesCurrent Opinion in Virology, 2015
The inflammasome is a caspase-1 containing complex that activates the proinflammatory cytokines IL-1β and IL-18 and results in the proinflammatory cell death known as pyroptosis. Numerous recent publications have highlighted the importance of inflammasome activation in the control of virus infection.
Christopher, Lupfer   +2 more
openaire   +2 more sources

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

open access: yes, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A   +173 more
core   +4 more sources

First report of naturally infected Sergentomyia minuta with Leishmania major in Tunisia

open access: yesParasites & Vectors, 2015
Background Many sand fly species are implicated in the transmission cycle of Leishmania parasites around the world. Incriminating new sand flies species, as vectors of Leishmania is crucial to understanding the parasite–vector transmission cycle in ...
Kaouther Jaouadi   +8 more
doaj   +1 more source

Immunity Against Leishmania major Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Zoonotic cutaneous leishmaniasis (ZCL) caused by Leishmania (L.) major infection is characterized by different clinical presentations which depend in part on the host factors.
Thouraya Boussoffara   +12 more
doaj   +1 more source

Online sex-seeking among Chinese heterosexual men who seek care in sexually transmitted infections clinics: a cross-sectional study

open access: yesArchives of Public Health, 2022
Background The Internet has become an important virtual venue for men who have sex with men to seek sexual partners, with a high potential threat to spread sexually transmitted infections (STIs).
Changchang Li   +9 more
doaj   +1 more source

Porcine innate and adaptative immune responses to influenza and coronavirus infections [PDF]

open access: yes, 2006
Both innate and adaptative immune responses contribute to the control of infectious diseases, including by limiting the spreading of zoonotic diseases from animal reservoirs to humans.
Asselin-Paturel   +35 more
core   +2 more sources

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