Results 81 to 90 of about 3,393,140 (353)

Correlation between Bioassay and Protein Misfolding Cyclic Amplification for Variant Creutzfeldt-Jakob Disease Decontamination Studies

mSphere, 2020
To date, approximately 500 iatrogenic Creutzfeldt-Jakob disease cases have been reported worldwide, most of them resulting from cadaveric dura mater graft and from the administration of prion-contaminated human growth hormone.
Maxime Bélondrade, Christelle Jas-Duval, Simon Nicot, Lilian Bruyère-Ostells, Charly Mayran, Laetitia Herzog, Fabienne Reine, Juan Maria Torres, Chantal Fournier-Wirth, Vincent Béringue, Sylvain Lehmann, Daisy Bougard   +11 more
doaj   +1 more source

Speculations on the clinical significance of asymptomatic viral infections [PDF]

, 2016
A detailed understanding of asymptomatic chronic viral infections is critical to analyse their pathogenesis, assess the severity and burden of disease and, where required, optimize public health control measures.
Gentile, Giuseppe, Micozzi, Alessandra
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A “One Health” surveillance and control of brucellosis in Azerbaijan

One Health & Risk Management, 2023
Introduction. The epidemiological situation of brucellosis in Azerbaijan remains concerning due to the presence of the infection among agricultural animals (cattle and small ruminants), which serve as the primary source of human infections.
Rita ISMAYILOVA, Natiq XALILOV, Masud KHATIBI   +2 more
doaj  

Zika virus induces strong inflammatory responses and impairs homeostasis and function of the human retinal pigment epitheliumResearch in context

EBioMedicine, 2019
Background: Zika virus (ZIKV) has recently re-emerged as a pathogenic agent with epidemic capacities as was well illustrated in South America. Because of the extent of this health crisis, a number of more serious symptoms have become associated with ZIKV
Yannick Simonin, Nejla Erkilic, Krishna Damodar, Marion Clé, Caroline Desmetz, Karine Bolloré, Mehdi Taleb, Simona Torriano, Jonathan Barthelemy, Grégor Dubois, Anne Dominique Lajoix, Vincent Foulongne, Edouard Tuaillon, Philippe Van de Perre, Vasiliki Kalatzis, Sara Salinas   +15 more
doaj   +1 more source

Effective elimination of Staphylococcal contamination from hospital surfaces by a bacteriophage-probiotic sanitation strategy: a monocentric study. [PDF]

, 2019
Persistent contamination of hospital surfaces and antimicrobial resistance (AMR) are recognized major causes of healthcare-associated infections (HAI). We recently showed that a probiotic-based sanitation (PCHS) can stably decrease surface pathogens and ...
BISI, Matteo, CASELLI, Elisabetta, D'ACCOLTI, Maria, LANZONI, Luca, MAZZACANE, Sante, SOFFRITTI, IRENE, VOLTA, Antonella   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Medical complexity and healthcare utilization among patients attending three U.S. post-COVID clinics

BMC Infectious Diseases
Background Patients who do not fully recover or develop new symptoms following SARS-CoV-2 infection require follow-up and sometimes seek care at specialized multidisciplinary care clinics.
Miriam A. M. Nji, Elizabeth M. Briones, Anindita Issa, Maureen Tierney, Jeanne Bertolli, Surendra Barshikar, Elizabeth R. Unger, Juan Wisnivesky, Quan Vu, David Quimby, Joseph Abrams, Nikhil Jagan, Sasha Manouchehripour, Martin Laguerre, Jennifer R. Cope   +14 more
doaj   +1 more source

The CD133+ Stem/Progenitor-Like Cell Subset Is Increased in Human Milk and Peripheral Blood of HIV-Positive Women

Frontiers in Cellular and Infection Microbiology, 2020
Human milk is a significant source of different CD133+ and/or CD34+ stem/progenitor-like cell subsets in healthy women but their cell distribution and percentages in this compartment of HIV-positive women have not been explored.
Jacqueline María Valverde-Villegas, Mar Naranjo-Gomez, Mar Naranjo-Gomez, Mélusine Durand, David Rutagwera, Anne-Sophie Bedin, Chipepo Kankasa, Ségolène Debiesse, Nicolas Nagot, Nicolas Nagot, Edouard Tuaillon, Edouard Tuaillon, Philippe Van de Perre, Philippe Van de Perre, Jean-Pierre Molès   +14 more
doaj   +1 more source

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy [PDF]

, 1999
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load.
Bangham, C.R.M., Bunce, M., Hall, S.E., Izumo, S., Jeffery, K.J.M., Kodama, D., Lloyd, A.L., Matsumoto, W., Nagai, M., Nowak, M.A., Ogg, G.S., Osame, M., Procter, J., Taylor, G.P., Usuku, K., Weber, J.N., Welsh, K.I.   +16 more
core   +2 more sources