Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Establishing Quality Control Procedures for Large-Scale Plasma Proteomics Analyses. [PDF]
Patterson KL +12 more
europepmc +1 more source
Simulation studies of time-control procedures for the advanced air traffic control system [PDF]
The problem of mixing aircraft equipped with time-controlled guidance systems and unequipped aircraft in the terminal area has been investigated via a real-time air traffic control simulation.
Alcabin, M. +3 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Review of robotic systems for thoracoabdominal puncture interventional surgery
Cancer, with high morbidity and high mortality, is one of the major burdens threatening human health globally. Intervention procedures via percutaneous puncture have been widely used by physicians due to its minimally invasive surgical approach. However,
Cheng Wang +10 more
doaj +1 more source
Addressing Algorithmic Errors in Data-Driven Border Control Procedures
The gradual digitization of EU migration policies is turning external borders into AI-driven filters that limit access to fundamental rights for people from third countries according to risk indicators.
Mirko Forti
doaj +1 more source
COVID-19 infection prevention and control procedures and institutional trust: Perceptions of Palestinian healthcare workers. [PDF]
El Sharif N, Ahmead M, Imam A.
europepmc +1 more source
Decoupled and linear quadratic regulator control of a large, flexible space antenna with an observer in the control loop [PDF]
An analysis is performed to compare decoupled and linear quadratic regulator (LQR) procedures for the control of a large, flexible space antenna. Control objectives involve: (1) commanding changes in the rigid-body modes, (2) nulling initial disturbances
Hamer, H. A. +2 more
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source

