The experience of European hospital-based health care workers on following infection prevention and control procedures and their wellbeing during the first wave of the COVID-19 pandemic. [PDF]
van Hout D +7 more
europepmc +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
STATISTICAL PROCEDURES IN THE QUALITY CONTROL OF THE GEARS
The production technology of the quality control, it’s strategy and planning in the process planning with the ability of aid with the computer is the important component of the improvement of the quality stability of the production according to the set ...
K. WECZEROWSKI, JA. UNIEJEWSKI
doaj
Adaptive p-value weighting with power optimality
Weighting the p-values is a well-established strategy that improves the power of multiple testing procedures while dealing with heterogeneous data. However, how to achieve this task in an optimal way is rarely considered in the literature.
Durand, Guillermo
core
Efficacy of statistical process control procedures to identify deviations in continuously measured physiological and behavioral variables in beef heifers resulting from an experimentally combined viral-bacterial challenge. [PDF]
Kayser WC +7 more
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Editorial: Demonstrating quality control (QC) procedures in fMRI
Paul A. Taylor +5 more
doaj +1 more source
STATISTICAL PROCEDURES IN THE QUALITY CONTROL OF THE GEARS
The production technology of the quality control, it’s strategy and planning in the process planning with the ability of aid with the computer is the important component of the improvement of the quality stability of the production according to the set ...
K. WECZEROWSKI, JA. UNIEJEWSKI
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

