Results 171 to 180 of about 28,382,436 (368)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Effect of a Job Demand-Control-Social Support Model on Accounting Professionals' Health Perception. [PDF]

open access: yesInt J Environ Res Public Health, 2018
Del Pozo-Antúnez JJ   +3 more
europepmc   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Internación compulsiva de usuarios de crack para el tratamiento de la dependencia: una revisión sistemática de la literatura

open access: yesMemorias del Instituto de Investigaciones en Ciencias de la Salud, 2019
El estudio tuvo como objetivo discutir los conflictos de la internación compulsiva de consumidores de crack. Se realizó una revisión sistemática sobre el tratamiento compulsivo. La búsqueda fue realizada en las bases de datos: Scopus, PubMed, SciELO, Web
Aldo Pacheco Ferreira   +5 more
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Videovigilancia en el centro de Madrid. ¿hacia el panóptico electrónico?

open access: yesRevista Teknokultura, 2014
En el centro de la ciudad de Madrid existen actualmente 147 cámaras de vigilancia controladas por la Policía Municipal, formando toda una malla de control digitalizado a través del cual la mirada panóptica se impone como un elemento más del espacio ...
Santiago Ruiz Chasco
doaj  

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