Results 101 to 110 of about 21,705,734 (300)
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Formal representation of GRAFCET to automatically generate control code
, 2014 Within the engineering of control code, model-based approaches become more and more important. Basically GRAFCET serves as a suitable modeling language but lacks an exhaustive formal representation of its structure and dynamic behavior since current ...
Schumacher, Frank, Fay, Alexander
core +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Practice-Oriented Formal Methods to Support the Software Development of Industrial Control Systems
, 2017 Formal specification and verification methods provide ways to describe requirements precisely and to check whether the requirements are satisfied by the design or the implementation.
Darvas, Daniel
core +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Challenges of Formal Social Security Systems in Sudan [PDF]
, 2011 The present paper discusses issues of challenges of social security systems in Sudan Following parameters advanced by ILO and UNCOSOC those systems are analyzed The conclusions focus on their applicability that faces axial difficulties mainly ...
Dr. Issam A.W. Mohamed
core
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Institutional changes and digital transformation of social control of deviant behavior
Наука. Культура. ОбществоThe article presents the results of a theoretical understanding of the transformations of social control of deviations, in particular, changes in its forms, principles and mechanisms. Methodologically, the work was based on S.
Yana A. Ardelyanova
doaj +1 more source
The application of repressive measurements toward juveniles in Republika Srpska [PDF]
Baština, 2019 The main problem of research in this paper is the aggressiveness of juveniles in Republika Srpska and the reaction of social subjects to such behaviour.
Milovanović Anatolij S.
doaj