Results 51 to 60 of about 21,705,734 (300)

Encounters between security guards and young people: the extent and biases of formal social control

Policing and Society, 2014
There is a distinct lack of knowledge about how the rise of private security relates to young people in adversarial encounters. Prior studies suggest that the policing of young people by police is a common occurrence and social biases exist. However, policing of young people by private security guards has gained much less attention.
Saarikkomäki Elsa, Kivivuori Janne
openaire   +3 more sources

Tercer Foro Nacional de Control Social: "La importancia del control social para la democracia" [PDF]

, 2009
Gestión del conocimientoParticipación ciudadana en Colombia. Rol del sector privado en la promoción del control social - CCB. Enfoque del Modelo de Control Social de la CCB. Líneas de trabajo en Control Social.
Cámara de Comercio de Bogotá
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

MOTIVATIONS, IMPORTANCE, CHALLENGES AND PERSPECTIVES OF SOCIAL CONTROL IN HEALTH

Cogitare Enfermagem, 2019
Purpose: To understand the motivations, importance, challenges and perspectives for acting as local health counselors in the Unified Health System.Method: A qualitative and descriptive study of the exploratory type conducted with 15 local health ...
Carlos Junglos, Felipa Rafaela Amadigi, Rosani Ramos Machado, Jacks Sorato   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Formal Specification of a Generic Separation Kernel [PDF]

, 2014
Item does not contain fulltextIntransitive noninterference has been a widely studied topic in the last few decades. Several well-established methodologies apply interactive theorem proving to formulate a noninterference theorem over abstract academic ...
Tverdyshev, Sergey, Nemouchi, Y., Tverdyshev, S., Blasum, H., Feliachi, Abderrahmane, Verbeek, F., Feliachi, A., Blasum, Holger, Schmaltz, J., Langenstein, Bruno, Verbeek, Freek, Wolff, B., Stephan, Werner, Langenstein, B., Stephan, W., Wolff, Burkhart, Havle, O., Havle, Oto, Schmaltz, Julien, Nemouchi, Yakoub   +19 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Attributes Of Police Leadership

Revista Criminalidad, 2019
The purpose of this article is to identify the attributes of police leadership and their relationships, associated with the dimensions of to be, to know, know-how, and know to be of the police officer. The methodological design used is of mixed type. For
Juan Carlos Nieto-Aldana, Julio César Acosta-Prado, Jesús María Cárdenas-Beltrán   +2 more
doaj