Results 31 to 40 of about 2,528,908 (305)

Facility-specific epidemiological characteristics of COVID-19 clusters across SARS-CoV-2 variant waves in South Korea

open access: yesInternational Journal of Infectious Diseases
Objectives: Few national-scale, multi-setting studies have compared COVID-19 cluster characteristics across successive SARS-CoV-2 variant periods. We assessed how outbreak duration, cluster size, and setting distribution shifted across six facility types
Hee Kyoung Kim   +5 more
doaj   +1 more source

A method for constructing an optimal control strategy in a linear terminal problem

open access: yesЖурнал Белорусского государственного университета: Математика, информатика, 2021
This paper deals with an optimal control problem for a linear discrete system subject to unknown bounded disturbances, where the control goal is to steer the system with guarantees into a given terminal set while minimising the terminal cost function. We
Dzmitry A. Kastsiukevich   +1 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Control Strategy of a Multiple Hearth Furnace Enhanced by Machine Learning Algorithms

open access: yes, 2019
An enhanced control strategy for a multiple hearth furnace for the purpose of kaolin production is developed and presented in this paper. Mineralogy-driven machine learning algorithms play a key role in the optimization strategy of the furnace.
Jämsä-Jounela, Sirkka-Liisa   +3 more
core   +1 more source

Arbovirus Transmission in Australia from 2002 to 2017

open access: yesBiology
Arboviruses pose a significant global public health threat, with Ross River virus (RRV), Barmah Forest virus (BFV), and dengue virus (DENV) being among the most common and clinically significant in Australia.
Elvina Viennet   +5 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Shift Strategy of Electric Drive Loader with Compound Control of Motor and Clutch

open access: yesShanghai Jiaotong Daxue xuebao, 2022
To give full play to the advantages of pure electric drive, and aimed at the transmission system of electric loader, the low efficiency hydraulic torque converter and reverse direction clutch of traditional models are cancelled.
REN Haoling, CAI Shaole, CHEN Qihuai, LIN Tianliang, LANG Bin
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

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