Results 191 to 200 of about 47,487,307 (346)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

An independently tunable dual control system for RNAi complementation in Trypanosoma brucei. [PDF]

PLoS One
Armstrong R, Romprey MJ, Raughley HM, Delzell SB, Frost MP, Chambers J, Garman GG, Anaguano D, Klingbeil MM.   +8 more
europepmc   +1 more source

FREQUENCY RESPONSE MEASUREMENTS OF THE EBWR AUTOMATIC STEAM BY-PASS VALVE CONTROL SYSTEM

, 1957
J.A. Jr. DeShong, E.S. Beckjord
openalex   +2 more sources

Control of adaptive immunity by the innate immune system

Nature Immunology, 2015
A. Iwasaki, R. Medzhitov
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Simulation Model for Hardware-in-the-Loop Tests of the ILR-33 AMBER Rocket Control System. [PDF]

Sensors (Basel)
Cieśliński D, Dziczkaniec R, Kierski J, Szczepański C, Welcer M.   +4 more
europepmc   +1 more source

S4G SHIP SERVICE ELECTRIC POWER AND CONTROL SYSTEMS DESIGN DESCRIPTION

, 1957
Eric Kallas, Jim Walz
openalex   +2 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts. [PDF]

NPJ Digit Med
Biermann P, Baier C, Vietor AC, Zacher B, Baumgartl T, von Landesberger T, Behnke M, Storck M, Petzold M, Kaase M, HiGHmed lnfection Control Study Group, Schlüter D, Marschollek M, Scheithauer S, Wulff A.   +14 more
europepmc   +1 more source

The American Social System. Social Control, Personal Choice and Public Decision

, 1957
Stuart A. Queen, William Nisbet Chambers, Charles M. Winston   +2 more
openalex   +2 more sources