Results 51 to 60 of about 5,820,048 (335)

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Neural-Network Based MPC for Enhanced Lateral Stability in Electric Vehicles

open access: yesIEEE Access
Distributed electric drive vehicles offer maneuver-ability but face stability challenges under different driving conditions. Model Predictive Control (MPC) algorithms can improve lateral stability, but their high computational demands hinder real-time ...
Ahmed Hassan   +4 more
doaj   +1 more source

Application of high-performance computing for determining critical components of an energy system [PDF]

open access: yesE3S Web of Conferences, 2020
This article presents a package for analyzing the energy system vulnerability developed with new technology for continuous integration, delivery, and deployment of applied software.
Edelev Aleksey   +3 more
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

FES-Assisted Walking with Spring Brake Orthosis: Simulation Studies

open access: yesApplied Bionics and Biomechanics, 2011
This paper presents a simulation of bipedal locomotion to generate stimulation pulses for activating muscles for paraplegic walking with wheel walker using functional electrical stimulation (FES) with spring brake orthosis (SBO).
R. Jailani   +3 more
doaj   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Reinforcement Learning for Semi-Active Vertical Dynamics Control with Real-World Tests

open access: yesApplied Sciences
In vertical vehicle dynamics control, semi-active dampers are used to enhance ride comfort and road-holding with only minor additional energy expenses. However, a complex control problem arises from the combined effects of (1) the constrained semi-active
Johannes Ultsch   +5 more
doaj   +1 more source

Adaptive Multi-Point Temperature Control for Microwave Heating Process via Multi-Rate Sampling

open access: yesSICE Journal of Control, Measurement, and System Integration, 2019
Microwave heating has been gradually extended to industrial material process from domestic microwave ovens because of its substantial advantages such as high-efficiency, pollution free, and selective heating.
Shan Liang   +4 more
doaj   +1 more source

Robust and dynamic transactive energy system using Tsypkin–Polyak theorem

open access: yesIET Smart Grid, 2018
In this study, a robust and dynamic transactive energy system in smart grid (SG) environment is proposed based on the Tsypkin–Polyak theorem. A key factor of the proposed system is to consider the uncertainties in electrical grid parameters.
Mohammad Rayati   +3 more
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

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