Results 81 to 90 of about 47,487,307 (346)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Real-time surrogate compensation architecture for machine-tool thermal error compensation with high-performance model

open access: yesDiscover Applied Sciences
Thermal error compensation based on high-performance (high-accuracy prediction of thermal errors under complex machining conditions and environments) models is of great significance to high-precision CNC machining. Currently, the high-performance thermal
Yubin Huang   +4 more
doaj   +1 more source

Prediction of Indoor Temperature and Relative Humidity Based on Cloud Database by Using an Improved BP Neural Network in Chongqing

open access: yesIEEE Access, 2018
For continuous improvement of productivity, accurate, stable, and reliable control of temperature and humidity is important in industrial production. Accurate prediction of air temperature and humidity can improve the predictability and stability of air ...
Xin Shi   +3 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Mixture Semisupervised Bayesian Principal Component Regression for Soft Sensor Modeling

open access: yesIEEE Access, 2018
In this paper, a mixture semisupervised Bayesian principal component regression-based soft sensor modeling method for nonlinear industrial process with multiple operating modes is presented. In many chemistry processes, part of output data samples may be
Pengbo Zhu   +3 more
doaj   +1 more source

Velocity vector control system augmented with direct lift control [PDF]

open access: yes, 1981
A pilot-controlled stability control system that employs direct lift control (spoiler control) with elevator control to control the flight path angle of an aircraft is described.
Kelly, W. W., Tisdale, H. F., Sr.
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Elliptical Model-Based Robust Pedestrian Pose Tracking by LiDAR via Bi-Level Moving Horizon Random Sample Consensus

open access: yesIEEE Access
Recent advancements in autonomous vehicle research have heightened the need for precise pedestrian pose tracking to ensure safe navigation. Utilizing LiDAR sensors, conventional bounding box (BB) methods are generally used but are sensitive to limb ...
Haziq Muhammad   +3 more
doaj   +1 more source

Enhancing Extractable Quantum Entropy in Vacuum-Based Quantum Random Number Generator

open access: yesEntropy, 2018
Information-theoretically provable unique true random numbers, which cannot be correlated or controlled by an attacker, can be generated based on quantum measurement of vacuum state and universal-hashing randomness extraction.
Xiaomin Guo   +5 more
doaj   +1 more source

Interactive Control System dalam Implementasi Strategi Penyelesaian Masalah Perusahaan [PDF]

open access: yes, 2017
Management control system is one way the company to establish a strategy and be a system that controls the performance of the company. However, each company has a strategy, problems and way of solving different problems.
Budianto, Y. (Yovan)   +1 more
core  

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