Results 211 to 220 of about 59,747,375 (260)

Covid-19 and Diaguita communities: structural inequalities and (inter)community strategies in the Santa María department (Catamarca, Argentina). [PDF]

Salud Colect
García Guerreiro L.
europepmc   +1 more source

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

Advanced Science, EarlyView.
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Tao Lu, Mina Nikolić, Baihao Huang, Deep Punj, Herlinde De Keersmaecker, Thibaut Van Acker, Wenjia Xie, Florian Vanlauwe, Phillip Blondeel, Liesl De Graeve, Félix Sauvage, Ranhua Xiong, Chaobo Huang, Frank Vanhaecke, Kevin Braeckmans, Stefaan C. De Smedt   +15 more
wiley   +1 more source

Development and evaluation of loop-mediated isothermal amplification (lamp) for rapid detection of campylobacter jejuni. [PDF]

Rev Peru Med Exp Salud Publica
Caro-Castro J, Orellana-Peralta F, Flores-León D, Cucho-Meza E, Gavilán RG, Quino W.   +5 more
europepmc   +1 more source

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Hospitalizations due to stroke and their relationship with Chagas disease: a population-based analytical study using data from the Hospital Information System of the Brazilian National Health System, Minas Gerais, Brazil, 2022. [PDF]

Epidemiol Serv Saude
Santos ACJ, Quintino ND, Silva JEFA, Nunes MDCP, Pereira JA, Pereira JA, Sabino EC, Mota AF, Haikal DS.   +8 more
europepmc   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Evaluation of the implementation of an intervention aimed at expanding Covid-19 testing, case telemonitoring and surveillance actions in Primary Health Care. [PDF]

Rev Saude Publica
Silva GAPD, Rossi TRA, Santana SF, Oliveira AB, Lima AMFS, Santos TS, Ramos ICN, Garcia CPC, Magno L, Dourado I, Silva LMVD.   +10 more
europepmc   +1 more source

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

Advanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang   +18 more
wiley   +1 more source

[Relationship between severity of hypomimia and basic emotion recognition in Parkinson's disease]. [PDF]

Rev Neurol
Cossini F, Cuesta C, Román K, Zambrano S, Rubinstein W, Politis D.   +5 more
europepmc   +1 more source