Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Motivation to exert effort dynamically adapts to reward context and environmental controllability. [PDF]
Li B +5 more
europepmc +1 more source
Erratum to: The Controllability of the Gurtin-Pipkin Equation: A Cosine Operator Approach [PDF]
Luciano Pandolfi, Pandolfi, Luciano
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Mechanisms underlying university students' perceived AI threat: the mediating roles of perceived controllability and perceived effort-reward imbalance. [PDF]
Liang Y, Du J.
europepmc +1 more source
The controllability of the Gurtin Pipkin equation: a cosine operator approach [PDF]
Pandolfi, Luciano
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Altered Driving Structures and Controllability Patterns of Brain Effective Networks in Mild Cognitive Impairment and Alzheimer's Disease. [PDF]
Xue J, Yan X, Wei J, Gao M, Liang K.
europepmc +1 more source
Controllability, ∗-controllability and stabilizability
openaire +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

