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Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Optimal stochastic tracking control for brain network dynamics. [PDF]

open access: yesCommun Biol
Dong K   +7 more
europepmc   +1 more source
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Control, and Control over Control

2021
This chapter draws attention to some examples of formal control mechanisms in professional service organizations. It mainly focuses on two main dimensions of control: control over workers (here in terms of recruitment and career development), and control over work (here in terms of time and billable hours on the one hand, and quality and work processes
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