In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
Development of the brain network control theory and its implications. [PDF]
Wu Z, Huang L, Wang M, He X.
europepmc +1 more source
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Low-dimensional controllability of brain networks. [PDF]
Ben Messaoud R +12 more
europepmc +1 more source
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley +1 more source
Leveraging natural language processing and machine learning to characterize psychological stress and life meaning and purpose in pediatric cancer survivors: a preliminary validation study. [PDF]
Sim JA +7 more
europepmc +1 more source
The "What" of Athletes' Goal Pursuit and Its Relationships to Goal-Related Processes and Well- and Ill-Being. [PDF]
Martínez-González N +3 more
europepmc +1 more source
The Pathway Relationship Between Physical Activity Levels and Depressive Symptoms in University Students Mediated by Cognitive Flexibility. [PDF]
Yu F +6 more
europepmc +1 more source
Gamification in education-teachers' perspectives through the lens of the theory of planned behavior. [PDF]
Leiss L +5 more
europepmc +1 more source
Optimizing piezoelectric actuator placement for enhanced vibration control using genetic algorithms. [PDF]
Wang S, Jin H, Wang Y, Huo J, Liu X.
europepmc +1 more source

