Results 51 to 60 of about 18,844,670 (344)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Journal of Economics & Management Strategy, 2007 What is the motivational effect of imposing a minimum effort requirement? Agents may no longer exert voluntary effort but merely meet the requirement. Here, we examine how such hidden costs of control change when control is considered legitimate. We study a principal-agent model where control signals the expectations of the principal and the agent ...
Schnedler, Wendelin, Vadovic, Radovan
openaire +7 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Glucontrol, no control, or out of control? [PDF]
Intensive Care Medicine, 2009 Sir: Preiser et al. [1] are to be congratulated on their randomized controlled multi-center trial on tight glycemic control (TGC) in critically ill patients. This trial adds to our knowledge of glucose control in intensive care units, but also poses a fascinating dilemma. While we need confirmation of the effects of TGC observed in Leuven, we notice at
Schultz, M.J. +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Controllability Metrics, Limitations and Algorithms for Complex Networks [PDF]
IEEE Transactions on Control of Network Systems, 2013 This paper studies the problem of controlling complex networks, i.e., the joint problem of selecting a set of control nodes and of designing a control input to steer a network to a target state.
F. Pasqualetti, S. Zampieri, F. Bullo
semanticscholar +1 more source
, 2017 Research provides the basis for scientific discovery and advancements in all areas of science. The process of discovery involves countless repetitions of the identical experiment in order to make a claim about the topic in question. In order to properly conduct an experiment that is similar or the same to one already executed, all of the variables must
openaire +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
On partial approximate controllability of semilinear systems
Cogent Engineering, 2014 In this paper, a sufficient condition for the partial approximate controllability of semilinear deterministic control systems is proved. Generally, the theorems on controllability are formulated for control systems given as a first-order differential ...
Agamirza E. Bashirov +1 more
doaj +1 more source
Group Controllability of Discrete-Time Time-Delayed Multiagent Systems with Multiple Leaders
Complexity, 2020 The group controllability is a unique distinct perspective and a further generalization of the controllability problem of discrete-time time-delayed multiagent systems (MASs) with multiple leaders.
Bo Liu +5 more
doaj +1 more source