Results 71 to 80 of about 18,844,670 (344)

Existence and controllability for stochastic evolution inclusions of Clarke's subdifferential type

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
In this paper, we investigate a class of stochastic evolution inclusions of Clarke's subdifferential type in Hilbert spaces. The existence of mild solutions and controllability results are given and proved by using stochastic analysis techniques ...
Yunxiang Li, Liang Lu
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Controllability of Fractional Complex Networks

open access: yesFractal and Fractional
Controllability is a fundamental issue in the field of fractional complex network control, yet it has not received adequate attention in the past.
Xionggai Bao, Weiyuan Ma, Xin Li
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Control functions of fuzzy controllers

open access: yesComputers & Mathematics with Applications, 2003
The study is concerned with the analysis of the geometry of a certain class of fuzzy controllers. Discussed are single input/single output and two input/single output fuzzy controllers realized in the following framework: (a) inference is implemented by means of the max-\(t\) composition, (b) rules are combined using various implication operators, (c ...
E.S. Lee   +3 more
openaire   +2 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

When does stress help or harm? The effects of stress controllability and subjective stress response on Stroop performance.

open access: yesFrontiers in Psychology, 2012
The ability to engage in goal-directed behavior despite exposure to stress is critical to resilience. Questions of how stress can impair or improve behavioral functioning are important in diverse settings, from athletic competitions to academic testing ...
Roselinde Kaiser Henderson   +4 more
doaj   +1 more source

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