This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao +6 more
wiley +1 more source
Interventions Targeting the Beef Feedlot Environment to Control Antimicrobial Resistance: A Mathematical Modelling Study. [PDF]
Beauvais WA +5 more
europepmc +1 more source
Multi‐scale Optimization on Interfacial Evaporative Cooling for Photovoltaic Performance Enhancement
This study presents a passive siphon‐driven interfacial evaporative cooling technology for photovoltaics. A multiscale multiphysics model is developed and validated experimentally. Results show that optimizing installation parameters reduces operating temperature by up to 22.3 °C and boosts power efficiency by 8.9%, offering a practical pathway for ...
Fuxiang Li +5 more
wiley +1 more source
Mechatronics Design of a Clinostat Agriculture Space System for Biomimetic Phyto-Growth in Microgravity (Phyto-G) and 3D-Motion Computer Simulation on Hydroponic Environment. [PDF]
Barreto R +4 more
europepmc +1 more source
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
Harnessing <i>Cannabis sativa</i> as a dual-use platform for biohydrogen production and pharmaceutical synthesis: a hypothesis and theory. [PDF]
Wang LP, Baban B.
europepmc +1 more source
Tensile‐strained bismuth nanosheets (TS‐BiNs) achieve a formate Faradaic efficiency of 92% at −1000 mA cm−2 and enable stable production of pure formic acid (HCOOH) in a solid‐state electrolyte reactor. Theoretical calculations reveal that the introduced strain lowers the energy barrier for *OCHO intermediate formation, fundamentally enhancing the ...
Shiqi Li +16 more
wiley +1 more source
LED Light Intensity Regulates Nitrogen Assimilation Enzyme Activity and Metabolic Responses in Iceberg and Leaf Lettuce (<i>Lactuca sativa</i> L.). [PDF]
Nguyen NTT +7 more
europepmc +1 more source
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Managing salinity stress through microclimate control to enhance tomato productivity in arid regions. [PDF]
Abbas F, Al-Naemi S.
europepmc +1 more source

