Results 251 to 260 of about 2,358,784 (358)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Controlled pesticide release from biodegradable polymers

Open Chemistry, 2014
Roy Anamika, Singh Sunil, Bajpai Jaya, Bajpai Anil   +3 more
doaj   +1 more source

Controlled Release Technologies for Diltiazem Hydrochloride: A Comprehensive Review of Solid Dosage Innovations. [PDF]

Pharmaceutics
Troches-Mafla E, Salamanca CH, Ciro Y.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Gel Delivery Systems in Dental Medicine: From Controlled Release to Regenerative Applications. [PDF]

Gels
Virvescu DI, Luchian I, Cioanca O, Rotundu G, Bida FC, Budala DG, Scurtu M, Surlari Z, Butnaru OM, Hancianu M.   +9 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Synergism Between Controlled-Release Fertilization and Microbial Bioinputs Modulates the Morphophysiological Quality of Prunus Rootstock Genotypes. [PDF]

Curr Microbiol
Paraginski JA, Moraes MP, Mayer NA, Bianchi VJ.   +3 more
europepmc   +1 more source

Preparation and controlled release properties of heterocyclic flavor CS/Zein microcapsules [PDF]

Miao Lai, Hongxiao Yu, Zhe Zhao, Xiaoxu Li, Yong Yue, Jingxian Sun, Heng Yue, Bin Yao, Tongxu Cui, Kun Wang, Gong Wei, Xinhua Song   +11 more
openalex   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Advancements in Polymer-Based Nanocarriers for Controlled Release of Nitric Oxide: Clinical Applications and Future Prospects. [PDF]

Int J Nanomedicine
Ying H, Zhou C, Liu X, Qin S, Chen L, Yu Y, Xia L, Lin H, Zhang S, Long H, Liang W.   +10 more
europepmc   +1 more source