Results 41 to 50 of about 32,304 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Development of Blockchain Technology [PDF]

open access: yesJournal of Advances in Computer Engineering and Technology, 2020
Blockchain technology is the first successful Bitcoin Network. It enables the ledger to become more decentralized and secure. Since it is not limited to bitcoin and controlled by third parties by government, corporations, or banks, the technology is ...
behnam Kiani Kalejahi   +2 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Contingency constrained TCSC and DG coordination in an integrated transmission and distribution network: A multi-objective approach

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy, 2023
Transmission System Operators (TSO) deploy Flexible AC Transmission Systems (FACTS) for congestion management in order to meet technical and multilateral power supply transactions.
Ahmad Abubakar Sadiq   +4 more
doaj   +1 more source

Community Trust Stores for Peer-to-Peer e-Commerce Applications

open access: yes, 2011
E-commerce applications have evolved from web-based selling via the Internet to selling in a P2P manner. P2P can enhance e-commerce applications to create lower cost systems compared to conventional client-server systems.
Taylor, Hamish   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

BFTM: Blockchain-Based MFA Framework for Secure Financial Transfers

open access: yesProceedings of the International Conference on Applied Innovations in IT
This paper proposes a blockchain-based multi-factor authentication (BMFA) framework designed to enhance the security of financial operations in decentralized systems.
Maha Alwan Alteef   +1 more
doaj   +1 more source

The determinants of ownership in M&As: An analysis of the stake purchases in Romanian acquisitions [PDF]

open access: yesContabilitate şi Informatică de Gestiune, 2019
Research question: The study aims to identify the microeconomic factors that influence the amount of stake purchased in Romanian acquisitions. Motivation: Romania is a market with potential and one of the fastest growing economies in the European Union ...
George Marian Aevoae   +2 more
doaj   +1 more source

Functional Markets in Yemen’s War Economy

open access: yesJournal of Illicit Economies and Development, 2021
Our article explores the economic activities of households operating in Yemen’s protracted conflict. We examine the growth and maturation of what we call the ‘Functional Economy’ in Yemen, in which Yemenis engage in economic transactions away from ...
R. Joseph Huddleston, David Wood
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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