Results 151 to 160 of about 3,809,070 (295)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of Novel Immunohistochemical Biomarkers for the Diagnosis of Celiac Disease Demonstrates the Utility of TCRδ Immunostaining. [PDF]

Diagnostics (Basel)
Lee H, Shenoy V, Gopalkaje P, Parsons S, Kaistha A, Soilleux EJ.   +5 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Differences in Income Growth Between People With Multiple Sclerosis and Controls: A Norwegian Cohort Study. [PDF]

Eur J Neurol
Høgset A, Simonsen CS, Flemmen HØ, Brunborg C, Broch L, Berg-Hansen P, Celius EG.   +6 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Chilean-type capital controls: A building block of the new international financial architecture? [PDF]

Taxes on short-term capital flows such as introduced in Chile and Slovenia during the 1990s in the form of unremunerated reserve requirements (URRs) on financial credits are under discussion as a remedy against adverse effects of volatile international ...
Buch, Claudia M.
core  

Phylogenetic Profiling of the Diabetic Foot Ulcer Microbiome of an Afro-Caribbean Population. [PDF]

Microbiologyopen
Ojeh N, Mohapatra BR, O'Shea M, Springer D, Ward J, Sallu M, Paquette N, Gooding K, Springer A, Peter Adams O.   +9 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A comparison of using online market panel members and traditional methods in control recruitment for a case-control study during a national outbreak of STEC O145, United Kingdom. [PDF]

Epidemiol Infect
King G, Rees C, Sawyer C, Hoban A, Inns T, Quinn O, Yanshi, Douglas A, Charlett A, Larkin L, Inzoungou-Massanga C, Awokoya M, Waghorn M, Olufon O, Nelson A, Williams C, Millar P, Dobosz C, Leckenby G, McKerr C, Nickbakhsh S, Balasegaram S.   +21 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source