Results 161 to 170 of about 396,003 (287)

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Controversies in endourology

open access: yesIndian Journal of Urology, 2013
Madhu S Agrawal
doaj   +1 more source

Orientation‐Confinement‐Engineered Stabilization of Ferroelectricity in HfO2 toward Maximum Polarization

open access: yesAdvanced Science, EarlyView.
Ferroelectric phase stability in Hf₀.5Zr₀.5O2 films is enhanced by confinement to the (111) crystal orientation, as demonstrated by first‐principles calculations and experiments. Polarization approaching its maximum value is achieved through selective ferroelectric switching paths, which are further tuned by oxygen vacancies and cation doping to ...
Fatoye Sawyerr   +14 more
wiley   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong   +13 more
wiley   +1 more source

Mechanism of Solid Solution‐Driven Texture Induced by Ag Doping in YBCO Superconductor

open access: yesAdvanced Science, EarlyView.
Ag‐doped YBCO with a designed concentration gradient is produced by dual‐material co‐extrusion and freeze‐drying. During annealing, Ag+ ions diffuse into Y123, substituting for Cu(1) and inducing c‐axis relaxation. This leads to the formation of [001]‐oriented YBCAO, creating a coherent interface that templates the textured growth of Y123. Consequently,
Fenyan Zhao   +4 more
wiley   +1 more source

Memristive Baffle Systems: Design, Simulation, and Applications

open access: yesAdvanced Science, EarlyView.
This study presents a nanoscale baffle‐system strategy for HfO2‐based memristors that controls oxygen‐vacancy transport through Al2O3 interlayers. Guided by multiscale simulation and experimental validation, the Al2O3 dual‐barrier configuration simultaneously enhances synaptic linearity and endurance.
Eun Young Kim   +9 more
wiley   +1 more source

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