Results 41 to 50 of about 396,003 (287)
Educació científica humanitzada [PDF]
, 2013 L'article analitza els fonaments de la ciència a l'escola i les seves interrelacions amb el concepte de Naturalesa de les ciències mitjançant l'ús dels seus antecedents històrics i fent referència a la història de la ciència.
Garrido Espeja, Anna, Özer, Ferah
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Revue Française des Sciences de l’Information et de la Communication, 2019 In this paper, we explore the interrelationships and reciprocal effects of Communication Studies with environmental controversies. As both a scientific object and a research path in Communication Studies since the 1990s, the environmental question very ...
François Allard-Huver
doaj +1 more source
Consensus statement from 2nd International Conference on Controversies in Vitamin D
Reviews in Endocrine & Metabolic Disorders, 2020 The 2nd International Conference on Controversies in Vitamin D was held in Monteriggioni (Siena), Italy, September 11-14, 2018. The aim of this meeting was to address ongoing controversies and timely topics in vitamin D research, to review available data
Andrea Giustina +14 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Kidney International, 2017 In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement plays a primary role in disease pathogenesis. Herein we report the outcome of a 2015 Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference where
T. Goodship +54 more
semanticscholar +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Marc teòric de les controvèrsies científiques : el cas de la sacarina / [PDF]
, 2002 Consultable des del TDXTítol obtingut de la portada digitalitzadaLa tesi doctoral s'emmarca dins el marc teòric dels estudis de Ciència, Tecnologia i Societat, concretament en els Estudis de Controvèrsies Científiques.
Vallverdú, Jordi
core +3 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Projets de Paysage, 2018 In this article, we have attempted to more clearly define the different roles assigned to controversies when these are used in teaching landscape architecture and science in order to develop a sense of citizenship.
Virginie Albe
doaj +1 more source