Results 91 to 100 of about 947,072 (293)

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

Taking Drugs to Help Others [PDF]

open access: yes, 2016
Every day the news shows us provoking stories about what's going on in the world, about events which raise moral questions and problems. In Philosophers Take On the World a team of philosophers get to grips with a variety of these controversial issues ...
Douglas, Thomas
core  

Controversial Issues in Congenital Nevi

open access: yesActas Dermo-Sifiliográficas (English Edition), 2009
Congenital melanocytic nevi are very common lesions that nevertheless pose many controversial questions. A systematic review of the literature suggests that the risk of developing melanoma on giant congenital melanocytic nevi (GCMN) is lower than previously thought given that, in the most recent series of GCMN, only 2 % of patients developed melanoma ...
S, Paradela   +2 more
openaire   +2 more sources

Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu   +10 more
wiley   +1 more source

Controversial issues in Norwegian social science classrooms

open access: yesJournal of Social Science Education
Highlights – Research discusses how civic education may alleviate social inequality in political efficacy. – Openness towards and awareness of controversial issues may play an important role.
Anders Kjøstvedt, Evy Jøsok
doaj   +1 more source

Jeannie Sowers Associate Professor of Political Science travels to Egypt [PDF]

open access: yes, 2013
Professor Sowers travelled to Egypt in February 2013 to continue her research on environmental issues and politics and to learn more about the ongoing political revolution that began in January 2011.With the assistance of a CIE travel grant funded by the
Sowers, Jeannie
core   +2 more sources

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló   +2 more
wiley   +1 more source

Femicide-certain controversial issues and comparative law review [PDF]

open access: yesRevija za kriminologiju i krivično pravo
During the last decades, the phenomenon of femicide has attracted the attention of both the scientific community and the wider public. However, despite the willingness to address the problem of gender-based violence, the number of murdered women is ...
Milica Kovačević, Marija Maljković
doaj   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

open access: yesAdvanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy