Results 41 to 50 of about 949,086 (301)

Taking Drugs to Help Others [PDF]

, 2016
Every day the news shows us provoking stories about what's going on in the world, about events which raise moral questions and problems. In Philosophers Take On the World a team of philosophers get to grips with a variety of these controversial issues ...
Douglas, Thomas
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Controversial issues in Swedish social studies education: Success and failure in teachers’ task perceptions

Journal of Social Science Education
Highlights: – The study examined teachers’ perceptions of success and failure in their teaching about controversial issues. – 18 interviewed teachers in civics in Swedish school years 7, 8, 9. – Relational aspects are decisive. – Values included
Anna Larsson, Kristina Ledman
doaj   +1 more source

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]

, 2012
The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J., Plate, Karl H., Scholz, Alexander   +2 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Cognitive styles: Controversial issues and research problems [PDF]

Национальный психологический журнал, 2016
The paper presents an analytical review of cognitive styles research, considering the problems of its theory, methodology, measurement and practical applications.
Natalia N. Volkova, Aleksey N. Gusev
doaj   +1 more source

Young People Developing Their Identity Perception and Values: How Can School Support Such a Process by Bringing in Controversial Issues?

Societies, 2023
This article draws upon group conversations with young people (11–19 years old) from Europe, focusing on the Nordic countries. The participants’ identity perception showed more aspects as the deliberative, non-structured conversations advanced.
Juliana Crespo Lopes, Bodil Liljefors Persson   +1 more
doaj   +1 more source

Drug Abuse the Most Important Issue Facing NH 2/14/17 [PDF]

, 2017
Misuse of drugs continues to be seen as the most important problem facing the state. New Hampshire residents are divided over several controversial issues being considered by the New Hampshire legislature including constitutional carry for concealed ...
Survey Center, UNH
core   +1 more source

Spin-Hall effect: Back to the Beginning on a Higher Level [PDF]

, 2005
The phenomena of the spin-Hall effect, initially proposed over three decades ago in the context of asymmetric Mott skew scattering, was revived recently by the proposal of a possible intrinsic spin-Hall effect originating from a strongly spin-orbit ...
Adagideli, Bernevig, Chalaev, Damico, Dimitrova, Dyakonov, Edelstein, Engel, Hankiewicz, Hirsch, Inoue, Inoue, Jairo Sinova, Kato, Mahn-Soo Choi, Mishchenko, Murakami, Murakami, Nikolić, Nomura, Nomura, Sheng, Sheng, Shuichi Murakami, Shun-Qing Shen, Sih, Sinova, Tse, Wunderlich   +28 more
core   +1 more source