Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide. [PDF]
Protein SciAbstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Hackney CM +12 more
europepmc +2 more sources
Cathepsins and their involvement in immune responses
Swiss Medical Weekly, 2010 The immune system is composed of an enormous variety of cells and molecules that generate a collective and coordinated response on exposure to foreign antigens, called the immune response. Within the immune response, endo-lysosomal proteases play a key
S Conus
doaj +1 more source
Developing Intensity-Duration-Frequency (IDF) Curves From Satellite-Based Precipitation: Methodology and Evaluation [PDF]
, 2018 Given the continuous advancement in the retrieval of precipitation from satellites, it is important to develop methods that incorporate satellite-based precipitation data sets in the design and planning of infrastructure.
Asquith W. H. +16 more
core +1 more source
Gustav Mahler, le dieu rittérien. William Ritter mélomane
Versants, 2019 Gustav Mahler représente sans aucun doute un cas particulier dans la vie et la carrière de critique d’art de William Ritter, contemporain du compositeur autrichien, et qui voit en ce dernier l’avènement d’une nouvelle ère musicale.
Céline Conus
doaj +1 more source
The association of right coronary artery conus branch size and course with ST segment elevation of right precordial leads and clinical outcome of acute anterior myocardial infarction [PDF]
Journal of Cardiovascular and Thoracic Research, 2017 Introduction: Coronary artery disease is the leading cause of death worldwide and electrocardiogram (ECG) is a reliable diagnostic tool to determine a myocardial infarction. The present study tried to compare the relationship between the ECG findings and
Samad Ghaffari +2 more
doaj +1 more source
Benefits of greenhouse gas mitigation on the supply, management, and use of water resources in the United States [PDF]
, 2014 Climate change impacts on water resources in the United States are likely to be far-reaching and substantial because the water is integral to climate, and the water sector spans many parts of the economy.
Boehlert, B +13 more
core +2 more sources
Resection of a conus medullaris hemangioblastoma: Case report
Interdisciplinary Neurosurgery, 2021 Background: Conus medullaris tumors are rare, as the majority of all spinal cord tumors occur in the cervical and thoracic regions. Hemangioblastomas of the spinal cord account for 3%–4% of all intramedullary spinal cord tumors and can be sporadic or ...
Reinier Alvarez +2 more
doaj +1 more source
Extreme events driving year-to-year differences in gross primary productivity across the US [PDF]
Biogeosciences, 2021 Solar-induced chlorophyll fluorescence (SIF) has previously been shown to strongly correlate with gross primary productivity (GPP); however this relationship has not yet been quantified for the recently launched TROPOspheric Monitoring Instrument ...
A. J. Turner +7 more
doaj +1 more source
Evolution of Conus peptide toxins: Analysis of Conus californicus Reeve, 1844 [PDF]
Molecular Phylogenetics and Evolution, 2010 Conus species are characterized by their hyperdiverse toxins, encoded by a few gene superfamilies. Our phylogenies of the genus, based on mitochondrial genes, confirm previous results that C. californicus is highly divergent from all other species. Genetic and biochemical analysis of their venom peptides comprise the fifteen most abundant conopeptides ...
Jason S, Biggs +10 more
openaire +2 more sources
In Vivo MRI Measurement of Spinal Cord Displacement in the Thoracolumbar Region of Asymptomatic Subjects with Unilateral and Sham Straight Leg Raise Tests. [PDF]
PLoS ONE, 2016 BACKGROUND:Normal displacement of the conus medullaris with unilateral and bilateral SLR has been quantified and the "principle of linear dependence" has been described.
M Rade +6 more
doaj +1 more source