Results 151 to 160 of about 16,038 (249)

A Transient Effect of Convalescent Plasma Therapy in a Patient with Severe Covonavirus Disease 2019: A Case Report. [PDF]

Infect Chemother, 2022
Baek AR, Choo EJ, Kim JY, Ha TS, Park SW, Shin HB, Park SK, Park JH, Kim T.   +8 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Convalescent plasma therapy for COVID-19 in patients with nasal catheter oxygen therapy. [PDF]

J Thorac Dis
Chen R, Zhang Y, Liu Y, Shi D, Wang C, Ye J, Yan D, Peng M, Lv D, Qian G.   +9 more
europepmc   +1 more source

COVID-19: Convalescent plasma as a potential therapy.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2020
van den Berg, Karin, Vermeulen, Marion, Glatt, Tanya Nadia, Wasserman, Sean, Barrett, Claire L, Peter, Jonny, Brittain, David, Louw, Vernon J   +7 more
openaire   +2 more sources

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial. [PDF]

Front Immunol
Alemany A, Ouchi D, Pradenas E, Aguilar R, Vidal M, Jimenez A, Millat-Martinez P, Corbacho-Monné M, Suñer C, Bassat Q, Baro B, Moncunill G, Mitjà O, COnV-ert Group of Authors, Blanco J, Dobaño C.   +15 more
europepmc   +1 more source

Pharmacokinetics of convalescent plasma therapy in a COVID-19 patient with X-linked Agammaglobulinemia. [PDF]

Clin Immunol Commun, 2022
Yates JL, Palat DS, Subik MK, Lee WT, McDonough KA, Conuel E.   +5 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Efficacy of convalescent plasma therapy in improving survival in non-immunized COVID-19 patients. [PDF]

Virol J
Portella Costa T, Bordin DM, Nóbrega Aoki M, Blanes L.   +3 more
europepmc   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source