Results 221 to 230 of about 16,038 (249)
Advanced Science, EarlyView.Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu +11 more
wiley +1 more source
Advanced Science, EarlyView.Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou +16 more
wiley +1 more source
Advanced Science, EarlyView.Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
Convalescent plasma therapy in patients with COVID-19 [PDF]
Transfusion and Apheresis Science, 2021 Passive antibody therapy has been used to immunize vulnerable people against infectious agents. In this study, we aim to investigate the efficacy of convalescent plasma (CP) in the treatment of severe and critically ill patients diagnosed with COVID-19.The data of severe or critically ill COVID-19 patients who received anti-SARS-CoV-2 antibody ...
Burhan Turgut +2 more
exaly +11 more sources
The Three Pillars of COVID-19 Convalescent Plasma Therapy [PDF]
Life, 2021 The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly around the world in the last year causing the coronavirus disease 2019 (COVID-19), which still is a severe threat for public health. The therapeutic management of COVID-19 is challenging as, up until now, no specific and efficient pharmacological therapy ...
Massimo Franchini +2 more
exaly +5 more sources
Effect of convalescent plasma therapy on mortality in moderate-to-severely Ill COVID-19 patients [PDF]
Transfusion and Apheresis Science, 2022 Amir Maroof Khan +2 more
exaly +2 more sources
Blood Endothelial-Cell Extracellular Vesicles as Potential Biomarkers for the Selection of Plasma in COVID-19 Convalescent Plasma Therapy [PDF]
Cells, 2022 Renee Bazin +2 more
exaly +2 more sources
Clinical Trial Subgroup Analyses to Investigate Clinical and Immunological Outcomes of Convalescent Plasma Therapy in Severe COVID-19 [PDF]
Mayo Clinic Proceedings Innovations, Quality & Outcomes, 2022 Praveen Singh +2 more
exaly +2 more sources
Convalescent plasma therapy in patients with severe COVID-19, A single-arm, retrospective study [PDF]
Microbial Pathogenesis, 2022 Ali Asadollahi-Amin +1 more
exaly +2 more sources
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[Value of convalescent plasma in the therapy of COVID-19].
Deutsche medizinische Wochenschrift (1946), 2023Convalescent plasma was discussed as a therapeutic option early in the course of the COVID-19 pandemic. However, until the onset of the pandemic, only the results of mostly small single-arm studies in other infectious diseases were available, which did not prove efficacy.
Sixten, Körper +2 more
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