Results 191 to 200 of about 21,991 (265)

Long Term Geomagnetic Variations and Whole-Mantle Convection Processes

American Geophysical Union (AGU) Fall Meeting, 2012
Biggin, A., Steinberger, B., Aubert, J., Suttie, N., Holme, R., Torsvik, T., van der Meer, D., van Hinsbergen, D.   +7 more
openaire   +2 more sources

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan, Marco P․ C․ Marques, Ana M. Azevedo, Daniel G. Bracewell, Stephen Goldrick   +4 more
wiley   +1 more source

Development of a Transient Wellbore Heat Transfer Model Validated with Distributed Temperature Sensing Data. [PDF]

Sensors (Basel)
Nakamoto R, Leggett S.
europepmc   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

Biological Reviews, EarlyView.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman, Daphne Cortese, Amelia Munson, Jan Lindström, Shaun S. Killen   +4 more
wiley   +1 more source

Enhanced methane chlorination via RuO₂-gas convection electrode with in-situ generated dynamical three-phase boundaries. [PDF]

Nat Commun
Fu Z, Zhou Y, Cao Z, Yang S, Huang L, Wu Z, Lu Y, Chen W, Weng X, Wang Z, Shi L.   +10 more
europepmc   +1 more source

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

Biotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal, Asingsa W. Arachchige, Annabelle J. Zahn, S. Ranil Wickramasinghe, Xianghong Qian, Andrew L. Zydney   +5 more
wiley   +1 more source

Energetically expensive dynamo action in Earth's basal magma ocean. [PDF]

Proc Natl Acad Sci U S A
Schaeffer N, Labrosse S, Aurnou JM.
europepmc   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Complex Fluids in a Multifractal Space: Scale Covariance and the Emergence of the Fractal Force. [PDF]

Entropy (Basel)
Rusu DI, Ghizdovat V, Ochiuz L, Rusu O, Oprea I, Dobreci L, Agop M, Vasincu D.   +7 more
europepmc   +1 more source

Metasurface Enhanced Photothermal Cement Foam for Robust and High‐Throughput Seawater Desalination

Carbon Energy, EarlyView.
Schematic of 3D metasurface‐enhanced cement foam for robust and high‐throughput seawater desalination. This study presents a cement‐based solar evaporator (CSE) fabricated in one step via viscoelastic lithography with simple negative pressure. In addition to boosting solar‐to‐vapor conversion efficiency via excellent light‐harvesting capacity, the ...
Jianjun Guo, Zhenxing Du, Wenqiang Zuo, Zhangyu Wu, Wei She   +4 more
wiley   +1 more source