Results 131 to 140 of about 290,776 (322)
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
The Relation of the National Society to the Engineering Profession: Address at the Annual Convention, Salt Lake City, Utah, July 20-1938 [PDF]
Henry E. Riggs
openalex +1 more source
Convention on certain conventional weapons
The Convention on Certain Conventional Weapons (CCWC) was concluded in 1980 as an “umbrella” treaty to which additional specific agreements might be attached in the form of protocols; at the time, three such protocols were concluded, dealing with: non-detectable fragments (Protocol I); mines and booby-traps (Protocol II and a technical annex); and ...
openaire +3 more sources
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
It is time to become serious about closing the global resource gap for FCTC implementation
Ryan Forrest, Sara Rose Taylor
doaj +1 more source
Program: Fall, 1938, Convention, Detroit, Mich., Hotel Statler [PDF]
Sherri Wolf+3 more
openalex +1 more source
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Sécurité syndicale et conventions collectives de travail [PDF]
Fabienne Tousignant
openalex +1 more source