Results 171 to 180 of about 531,785 (337)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

How are sexual orientations, gender identities and expressions, and sex characteristics (SOGIESC) addressed in UN conventions, treaty bodies, and decisions: a scoping review. [PDF]

Global Health
Seppey M, Bodryzlova Y, Mac-Seing M, Girard G, Zarowsky C.   +4 more
europepmc   +1 more source

The Implications of the Arbitration Convention : A step back for the European Community or a step forward for elimination of transfer pricing related double taxation?

, 2006
Andreas Bernath
openalex   +1 more source

Convention on the Recognition and Enforcement of Foreign Judgments in Civil or Commercial Matters: A New Contribution of the Hague Conference on Private International Law to the Unification of International Civil Procedure

, 2020
Gennadii Zirat
openalex   +1 more source

131st SMPTE Technical Conference and Equipment Exhibit: Los Angeles Convention Center, Calif., October 21–25, 1989 [PDF]

, 1989
John Baptista, Alan Godber, Howard Zare, Stanley N. Baron, Juan C. Samper, Eastman Kodak, V-Series ; Paintbox, L Richard, Allman, Gregory Breedlove, Michael Chewey, Eugene Leonard, , Eidak Corp.-Lrg Labs, Roslyn, N, Glenn Kennel, Leroy Demarsh, John Norris, Eastman Kodak Co, ) Ursa (telecine, Colin Ritchie, Peter Swinson, Rank Cintel Inc, ; Hunt, Glenn Kennel, Kodak Eastman, Co   +26 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Initial risk assessment under Regulation A-4 of the Ballast Water Management Convention for Belgium using the joint HELCOM/OSPAR Harmonised Procedure [PDF]

, 2015
Vliz
openalex  

'God Said to Abraham/Kill Me a Son': Why the Insanity Defense and the Incompetency Status are Compatible with and Required by the Convention on the Rights of Persons with Disabilities and Basic Principles of Therapeutic Jurisprudence

, 2015
Michael L. Perlin
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Between Protection and Destruction: The Legal Tension Between Military Necessity and Cultural Heritage Protection in International Humanitarian Law. [PDF]

F1000Res
El Baroudy J, Albakjaji M, Khater M.
europepmc   +1 more source