Results 181 to 190 of about 2,139,382 (339)
Equitable access to cochlear implants: a perspective on social justice and international obligations. [PDF]
Suazo-Díaz P +3 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Awareness of Amalgam and Safe Removal Techniques Among Dentists in Turkey: A Cross-Sectional Study. [PDF]
Yikici Çöl C +2 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Correction: Effect of a loss of the mda5/ifih1 gene on the antiviral resistance in a Chinook salmon Oncorhynchus tshawytscha cell line. [PDF]
Collins C +8 more
europepmc +1 more source
Conventions and Democracy [PDF]
The purpose of this article is to consider how the introduction of a special\ud Parliamentary select committee could extend democratic influences in the\ud evolution of binding non-legal constitutional practices.1 Following a\ud consideration of other possible avenues of reform, it will be suggested that\ud whilst political actors should continue both ...
openaire +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
When culture meets child rights: Confucian ethics and legal challenges in mental health protection for minors in China. [PDF]
Li T, Zheng L.
europepmc +1 more source

