Results 61 to 70 of about 2,094,503 (306)
Conventional and non-conventional Drosophila Toll signaling [PDF]
Developmental & Comparative Immunology, 2014 The discovery of Toll in Drosophila and of the remarkable conservation in pathway composition and organization catalyzed a transformation in our understanding of innate immune recognition and response. At the center of that picture is a cascade of interactions in which specific microbial cues activate Toll receptors, which then transmit signals driving
Lindsay, Scott A, Wasserman, Steven A
openaire +4 more sources
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
AAPS OpenThis study introduces an innovative approach to automatically analyzing 1H nuclear magnetic resonance (NMR) data, integrating a quantum mechanical spectral analysis (QMSA) to enhance efficiency over manual data analysis in NMR.
Sunil Babu Paudel +5 more
doaj +1 more source
A Study of the 1988 NAEA and Its Accessibility to Delegates Experiencing Disabilities [PDF]
, 1989 People experiencing disabilities are no longer content to be treated as victims, objects of pity, and passive recipients of charitable impulses. They are aggressively and actively brining discriminatory policies and environments to the public’s attention.
Blandy, Doug
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian +7 more
wiley +1 more source
A New Approach to United States Enforcement of International Arbitration Awards [PDF]
, 1968 Pursuant to ratification of the World Bank Convention on the Settlement of Foreign Investment Disputes, the United States Congress passed the Convention on Settlement of Disputes Act of 1966, utilizing a full faith and credit approach to enforce arbitral
core +1 more source
Inspiral waveforms for spinning compact binaries in a new precessing convention
, 2016 It is customary to use a precessing convention, based on Newtonian orbital angular momentum ${\bf L}_{\rm N}$, to model inspiral gravitational waves from generic spinning compact binaries.
Gopakumar, Achamveedu, Gupta, Anuradha
core +1 more source