Results 101 to 110 of about 210,367 (300)

Who Benefits from CGIAR Germplasm? [PDF]

open access: yes, 1994
News release announcing CGIAR-FAO agreement regarding the future trusteeship role of the CGIAR centers in keeping with the Convention on Biological Diversity, under which the Centers confirm that they will not allow any intellectual property protection ...
CGIAR Secretariat
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A common basis for facilitated legitimate exchange of biological materials proposed by the European Culture Collections' Organisation

open access: yesInternational Journal of the Commons, 2009
Being charged with the task of accessioning and supplying of living microbiological material, microbial culture collections are institutions that play a central role between the interests of a variety of user communities.
Dagmar Fritze
doaj   +1 more source

Galapagos coral conservation: impact mitigation, mapping and monitoring. Guest editorial [PDF]

open access: yes, 2009
This special edition of Galapagos Research is devoted to research outcomes from the U.K. Government’s Darwin Initiative project 14-048 entitled Galapagos Coral Conservation: Impact Mitigation, Mapping and Monitoring. The Darwin Initiative was established
Banks, S., Dawson, T.P., Henderson, S.J.
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

SAMUDRA Report No. 57, November 2010 [PDF]

open access: yes, 2010
Mackerel mayhem: On the ongoing dispute in northern Europe over the boom in mackerel stocks. Small and mighty: The Banjul civil society declaration on sustainable livelihoods in African fisheries.

core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

India knows its invasive species problem but this is why nobody can deal with it properly [PDF]

open access: yes, 2016
In 1993, the International Convention on Biological Diversity (CBD) came into legal effect to conserve biological diversity, ensure that biological diversity would be used sustainably and that its benefits would be shared equitably.
Ankila Hiremath, J, Krishnan, Siddhartha
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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