Results 101 to 110 of about 408,939 (300)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Recent Trends in the Argumentation of the European Court of Human Rights on Children’s Rights
Public Governance, Administration and Finances Law ReviewThe European Convention on Human Rights (ECHR) is a key human rights treaty ratified by all EU member states and beyond. Although it does not focus specifically on children, it includes relevant provisions and obliges states to protect the rights of all ...
Ágnes Lux
doaj +1 more source
Tradeoffs in Formulating a Consistent National Policy on Adoption [PDF]
Just as the courts must consider the tradeoff between the best interest of the child and parental rights in involuntary termination of parental rights, policy on international adoption must consider the tradeoffs between the best interest of the child ...
Daniel Pollack, Mary Eschelbach Hansen
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AN INVESTIGATION OF ALBANIAN ORPHANS’ ACCOMMODATION AND EDUCATION ISSUES FROM A LEGAL PERSPECTIVE [PDF]
, 2014 Among the most vulnerable groups in Albania, orphans are the ones who have been encountering a lot of problems due to the neglect of the government on providing the support they need. This work focuses on the Albanian orphans’ accommodation and education
Uka, Ana
core
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
The Convention On The Rights Of The Child: The Necessity Of Adding A Provision To Ban Child Marriages [PDF]
, 1998 The United Nations Convention on the Rights of the Child [hereinafter CRC ], adopted on November 20, 1989 is considered by many to be a comprehensive ...
Askari, Ladan
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Systematic ReviewsBackground The concept of children’s rights emerged during the 1980s and emphasised the role of children as active participants in matters which concern them.
Sahar Mazied Alshammari +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source