Results 51 to 60 of about 727,619 (306)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Pelatihan Akuntansi Bank Transaksi Back Office Bank Konvensional Bagi SMK Unitomo Surabaya

Dinamisia, 2020
Senior Vocational School of Unitomo Surabaya is one of scholl in Surabaya that have cooperated with STIE Perbanas Surabaya. One of majoring in Senior Vocational School of Unitomo Surabaya is accounting.
Evi Sistriyarini, Herizon, Carolyn Lukita Sembiring   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

"Have Banks Contributed to Efficient Management in Japan's Manufacturing?" [PDF]

This paper statistically reexamines the conventional view that the main bank relationship has been an important element of corporate governance in Japan.
Akiyoshi Horiuchi, Masaharu Hanazaki
core   +3 more sources

PERFORMANCE COMPARISON BETWEEN ISLAMIC BANKS AND CONVENTIONAL BANKS IN INDONESIA

EKUITAS (Jurnal Ekonomi dan Keuangan), 2018
Penelitian ini bertujuan untuk mengetahui pengaruh makroekonomi yang diukur oleh inflasi, net ekspor dan suku bunga Bank Indonesia (BI rate)  terhadap kinerja perbankan serta melakukan analisis perbandingan kinerja perbankan yang diukur oleh capital adequacy ratio (CAR), loan to deposit ratio (LDR) dan non performing loan (NPL) antara bank umum syariah
Dudi Rudianto, Tetty Sari Rahmiati
openaire   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Analysis of Comparative Fiqh: Conventional Bank Versus Islamic Bank

Ulumuddin
What happens in the community about the concept of bank interest and profit sharing there are different perspectives. Bank interest is often regarded as usury in Islam, as it is contrary to Sharia principles.
Lutfiyah Lutfiyah, Nazih Sadatul Kahfi Nazih, Nilal Muna Fatmawati, Muhammad Abdul Rahman Hakim, Muhyar Fanani   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Contribution of conventional bank lending for agricultural sector in Indonesia

Jurnal Perspektif Pembiayaan dan Pembangunan Daerah, 2021
This study examines the determinant contribution of conventional bank lending for the agricultural sector in Indonesia. The analysis method used in this research is the Vector Correction Model (VECM).
Hari Setia Putra, Yunnise Putri, Ali Anis, Zul Azhar   +3 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source